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Skin Lighteners: Safety & Efficacy
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havana8
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Wed May 02, 2012 9:07 am      Reply with quote
Since many are interested in skin lighteners, as suggested on another thread we are opening a new topic to discuss available options as well as their safety and efficacy.

Where should we start? Smile
rileygirl
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Wed May 02, 2012 12:41 pm      Reply with quote
There is a reason HQ is still the Gold standard for pigmentation issues - because it works. (I am talking about stubborn, deep hyperpigmentation here, not something to lighten freckles, even up the skin tone, etc.) There may be "safer" ingredients, but I don't think any of them have been proven to work as well as HQ, which is why this ingredient is still around. Aren't the safety issues only a factor when you are talking about a Large dose of HQ (well above the Rx 4% strength), as well as internal use of the ingredient, or when using it for longer than 3-4 months at a time?

ETA: I don't have pigmentation issues any longer (Obagi wiped all that out for me). But, I did want to toot your horn/product, Dr. J, as it has been only 2 1/2 weeks since starting it, and my skin is taking on a nice "even" look for lack of a better word. I am not sure if that is due to reduced redness, or what, but I am liking the results. However, I am not sure if they would truly work on someone with deeper pigmentation issues, which is where HQ fits in, IMO.
Kassy_A
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Wed May 02, 2012 12:49 pm      Reply with quote
Wow, I totally agree with everything DrJ wrote... Very Happy

But, some folks are looking to turn brown skin into white, where as hydroquinone (as dangerous as it is long term) seems to have worked for some. (Michael Jackson, Beyonce, Tyra and a few others come to mind) And no I don't have proof, so please no jumping on me.. But I know what I see with my own eyes!

Then we have those who 'just' want to deal with melasma and such, and even though there are safer alternatives, people are always up for more instant gratification products...(Even at the detriment of their health.)

What about short term use of hydroquinone at no more than 4% for say 6 months? Kind of as a jump start if you will... And then ingredients like; arbutin, kojic acid, niacinamide, licorice root, retinols and maybe even L-AA.

I mention L-AA simply because I haven't experienced even one tan line since I've used it consistently head to toe.. (I avoid the sun when I can and don't use sunscreen regularly.. AND I live in south Florida.) And NO, I am not suggesting anybody forgo sunscreen, but I am suggesting that a well formulated antioxidant serum affords UV protection (in addition to your sunscreen) in my experience..

Nice topic idea! I'll see if I can dig up any of my past research that might be of value..

ETA: I just saw your post Riley.. I followed your Obagi posts for years and totally respect both your use of Obagi and the responsible way you share your knowledge of the products.. I salute you my girl.. Very Happy It is a younger generation of gals, who might be using for the wrong reasons, or with reckless abandon that I had in mind..

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DarkMoon
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Wed May 02, 2012 12:57 pm      Reply with quote
melanie haber wrote:
rileygirl wrote:
ETA: I don't have pigmentation issues any longer (Obagi wiped all that out for me). But, I did want to toot your horn/product, Dr. J, as it has been only 2 1/2 weeks since starting it, and my skin is taking on a nice "even" look for lack of a better word. I am not sure if that is due to reduced redness, or what, but I am liking the results. However, I am not sure if they would truly work on someone with deeper pigmentation issues, which is where HQ fits in, IMO.

Wait -- what is DrJ's product?


Cellese AnteAge:

http://www.essentialdayspa.com/forum/viewthread.php?tid=45400

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DrJ
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Wed May 02, 2012 2:35 pm      Reply with quote
jom wrote:
rileygirl wrote:


ETA: I don't have pigmentation issues any longer (Obagi wiped all that out for me). But, I did want to toot your horn/product, Dr. J, as it has been only 2 1/2 weeks since starting it, and my skin is taking on a nice "even" look for lack of a better word. I am not sure if that is due to reduced redness, or what, but I am liking the results. However, I am not sure if they would truly work on someone with deeper pigmentation issues, which is where HQ fits in, IMO.



It is probably due to the niacinamide in the serum.


Niacinamide is one key, but not the only one. Vit A helps too (part of the original Klingman combo formula of HQ, retinol & corticosteroid). Several years we had a formulation with no niacinamide or retinoids and we saw the same results, although we think all these are additive).

A solution of stem cytokines alone has this color smoothing effect. Several cytokines are at work, reducing inflammation (which has a role in may dyschromias), altering melanin production, and inhibiting tyrosinase.

At one point we tested alpha arbutin in the AnteAGE accelerator as an extra brightening agent, but abandoned it as being perhaps "too much" for most people
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