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Pycnogenol
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Lacy53
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Fri Sep 06, 2013 7:47 pm      Reply with quote
AngelaE8654 wrote:

Pycnogenol significantly improved hydration and elasticity of skin.

CONCLUSIONS:

This study provides skin-physiological and for the first time molecular evidence that Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity. These effects are most likely due to an increased synthesis of extracellular matrix molecules such as hyaluronic acid and possibly collagen. Pycnogenol supplementation may thus be useful to counteract the clinical signs of skin aging.

http://www.ncbi.nlm.nih.gov/pubmed/22270036


Although no conflict of interest was declared for this lone study, I note that the researchers are listed as: Marini A. · Grether-Beck S. · Jaenicke T. · Weber M. · Burki C. · Formann P. · Brenden H. · Schönlau F. · Krutmann J.

Burki and Schönlau are employed by Horphag Research, Cointrin/Geneva, Switzerland, which is described as:

the exclusive worldwide supplier of Pycnogenol® French maritime pine bark extract. Based in Geneva, Switzerland, Horphag has the exclusive rights to market and sell Pycnogenol® and works with hundreds of companies to help them develop innovative and effective Pycnogenol® product formulas.

http://www.linkedin.com/company/horphag-research

This is not independent research, so the results should be cautiously interpreted. The study needs to be independently replicated before the findings are accepted.

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Lacy53
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Fri Sep 06, 2013 7:59 pm      Reply with quote
AngelaE8654 wrote:
It's not very often that we get the FDA or the National Institutes of Health or any of those type of agencies to agree that a nutritional supplement actually does do good things for our skin or whatever. This is very rare and in this case, the NIH agrees that this supplement really and truly does improve hydration and elasticity of skin. Except for situations where a person may be allergic to it or have some other health reason not to take it, I would recommend it to anyone who wants to improve their skin or to maintain great skin if that's what they're blessed with. Smile


I didn't see any federal agency agree that it does anything for skin or whatever. I did find the Cochrane Review which states:

MAIN RESULTS:
This review includes 15 trials with a total of 791 participants that have evaluated Pycnogenol(®) for the treatment of seven different chronic disorders. These included asthma (two studies; N = 86), attention deficit hyperactivity disorder (one study; N = 61), chronic venous insufficiency (two studies; N = 60), diabetes mellitus (four studies; N = 201), erectile dysfunction (one study; N = 21), hypertension (two studies; N = 69) and osteoarthritis (three studies; N = 293). Two of the studies were conducted exclusively in children; the others involved adults.Due to small sample size, limited numbers of trials per condition, variation in outcomes evaluated and outcome measures used, as well as the risk of bias in the included studies, no definitive conclusions regarding the efficacy or safety of Pycnogenol(®) are possible.

AUTHORS' CONCLUSIONS:
Current evidence is insufficient to support Pycnogenol(®) use for the treatment of any chronic disorder. Well-designed, adequately powered trials are needed to establish the value of this treatment.

http://www.ncbi.nlm.nih.gov/pubmed/22336841

The Medline Plus article doesn't mention skin conditions specifically, but does state Insufficient evidence to rate effectiveness for Aging.

http://www.nlm.nih.gov/medlineplus/druginfo/natural/1019.html

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Thu Sep 19, 2013 12:58 pm      Reply with quote
bethany wrote:
AnnieR wrote:
I guess just by opening up a capsule? Mmmmm... might have to try that. I have new shipment coming in next week since I just ran out. This was a good reminder! I will check it out and get back to you.


Will it really penetrate that way?


as long as the capsules does not contain any irritants and one dissolves the content properly, it should be fine, however for better penetration it should be mixed in an emulsion as water/toner ll evaporate quickly....
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