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Fri Jan 24, 2014 4:11 pm |
And here is some research about collagen supps tho the source of the collagen isnt specified. (Kudos to another member for finding these studies!):
Skin Pharmacol Physiol. 2013 Aug 14;27(1):47-55. [Epub ahead of print]
Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study.
Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S.
Source
Department of Dermatology, University of Kiel, Kiel, Germany.
Abstract:
Various dietary supplements are claimed to have cutaneous anti-aging properties; however, there are a limited number of research studies supporting these claims. The objective of this research was to study the effectiveness of collagen hydrolysate (CH) composed of specific collagen peptides on skin biophysical parameters related to cutaneous aging. In this double-blind, placebo-controlled trial, 69 women aged 35-55 years were randomized to receive 2.5 g or 5.0 g of CH or placebo once daily for 8 weeks, with 23 subjects being allocated to each treatment group. Skin elasticity, skin moisture, transepidermal water loss and skin roughness were objectively measured before the first oral product application (t0) and after 4 (t1) and 8 weeks (t2) of regular intake. Skin elasticity (primary interest) was also assessed at follow-up 4 weeks after the last intake of CH (t3, 4-week regression phase). At the end of the study, skin elasticity in both CH dosage groups showed a statistically significant improvement in comparison to placebo. After 4 weeks of follow-up treatment, a statistically significantly higher skin elasticity level was determined in elderly women. With regard to skin moisture and skin evaporation, a positive influence of CH treatment could be observed in a subgroup analysis, but data failed to reach a level of statistical significance. No side effects were noted throughout the study. © 2013 S. Karger AG, Basel.
CLINICAL STUDIES – SKIN
Results of a study evaluating the use of a dietary supplement formula in the management of age-related skin changes in women with moderate to severe wrinkling of the periorbital area.
Kantor I., Donikayan L., Simon R., & Wollschlaeger B. (2002)
Journal of the American Nutraceutical Association. 5(2):
American researchers wanted to assess the safety and effectiveness of a collagen based dietary supplement for the improvement of age-related degenerative skin changes in women. 38 women aged between 35-65 years participated in the eight week study. The key target of their research was to assess the improvement to periorbital (area around the eye) wrinkling, aging, sagging and puffiness and overall periorbital facial aging. Results showed that the dietary collagen formulation resulted in a highly statistically significant improvement in periorbital wrinkling, in periorbital aging and in periorbital overall facial aging. The researchers also found that the collagen based formula was very safe with minimal adverse effects reported.
( 888ageless.com/pdf/jana.pdf )
Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts.
Ohara H., Ichikawa S., Matsumoto H., Akiyama M., Fujimoto N., Kobayashi T., Tajima S. (2010)
The Journal of Dermatology. 37: 330-338
Leading Japanese skin researchers investigated the influence of collagen-derived peptides on human skin cells & structure. The researchers hypothesized that supplementation with collagen hydrolysate potentially changes extracellular matrix metabolism in the skin. Results in this in vitro study confirmed this hypothesis. Researchers found that collagen derived peptides not only stimulate skin cell production, but may also stimulate hyaluronic acid (the body’s own moisturiser) synthesis. From this, the researchers concluded that oral ingestion of collagen hydrolysate may lead to more viscous and elastic skin resulting in improvement of skin appearance.
(www.ncbi.nlm.nih.gov/pubmed/20507402 )
Identification of food-derived collagen peptides in human blood after oral ingestion of gelatine hydrolysates.
Iwai K., Hasegawa T., Taguchi Y., Morimatsu F., Sato K., Nakamura Y., Higashi A., Kido Y., Nakabo Y., & Ohtsuki K. (2005)
Journal of Agricultural and Food Chemistry. 53: 6531-6536
The objective of this study was to see if food-derived collagen peptides were absorbed into the bloodstream. The research showed that several food-derived collagen peptides appeared in human blood after oral ingestion of some gelatine hydrolysates. Negligible amounts of the peptide form of hydroxypoline (Hyp) were observed in human blood before ingestion. After oral ingestion, the peptide form of Hyp significantly increased. The researchers concluded that collagen peptides may act as a messenger and trigger the synthesis and reorganisation of new collagen by stimulating fibroblast cells.
(www.ncbi.nlm.nih.gov/pubmed/16076145 )
Effects of oral ingestion of collagen peptide on the skin.
Koyama Y., Sakashita A., Kuwaba K., Kusubata M. (2006)
Fragrance Journal. 34: 82-85
Researchers studied the effects of daily ingestion of collagen on skin hydration and collagen fibrils in the dermis. When healthy Japanese women ingested collagen peptides over 60 days, it was shown that the absorption ability of the outer most layer of the skin increased (& thus improved skin function) over the placebo group. The researchers also administered collagen peptide orally to pigs daily for 62 days. Results showed the density of fibroblasts and diameter and density of collagen fibrils in the dermis was significantly larger than that of pigs not fed collagen. Taken together, the researchers concluded that these results suggest the daily ingestion of collagen peptide improves the function of both the epidermis and the dermis of the skin.
( sciencelinks.jp/j-east/article/200614/000020061406A0482755.php )
7.5g and 8.5g were ingested 3xday for 2 weeks and then 2xday for 2 additional weeks in this study (so 22.5g at least or 22,500mg):
888ageless.com/pdf/jana.pdf
And in this study, 2.5 g or 5.0 g of CH or placebo once daily for 8 weeks was given.
www.ncbi.nlm.nih.gov/pubmed/23949208
Is drinking collagen a Magic Bullet? Of course not, but its one more weapon in the arsenal. Depends how militant you are I guess!
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_________________ ✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Thu Jan 30, 2014 2:26 pm |
I've been taking Medelys Supreme Collagen (http://www.aviva.ca/shop/products.asp?itemid=4784&catid=75) in conjunction with Health Force Chlorella Manna (http://www.iherb.com/HealthForce-Nutritionals-Chlorella-Manna-10-58-oz-300-g/37600) and now I have amazingly long eyelashes I even quit using Lumugan (bimatoprost) because I do not need it now. I have no idea which supplement contributes to the growth of my lashes as I started taking them at the same time.
Medelys Supreme Collagen
Ingredients: MEDICINAL INGREDIENTS PER 15 ML: Amino acids and peptides complex * of hydrolysed Collagen (Bovin sp.) 5 000 mg Glucosamine sulphate 1 000 mg Chondroitin sulphate 500 mg MSM 400 mg *Amino acids: glycine, proline, hydroxyproline, glutamic adic, alanine, arginine, aspartic acid, lysine, serine, valine, leucine, phenylalanine, isoleucine, hydroxylysine, tyrosine, methionine, histidine, cysteine. |
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