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Thu Sep 12, 2013 5:26 pm  |
Hi fawnie, where did you buy your 50 k dalton HA? Thank you |
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Thu Sep 12, 2013 5:40 pm |
| Daler, from Evonik. |
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✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Thu Sep 12, 2013 5:45 pm |
| fawnie wrote: |
| Daler, from Evonik. |
Fawnie!!  You might have just solved the Sqoom gel dilemma! 
(By the way, I've looked over your website and your products look lovely! Maybe you can formulate a nice, affordable version of the Sqoom gels for us?)
Edited to add: Evonik requires you to register with a company name, and they probably have a required minimum purchase, so I guess it remains to be seen if we've solved the Sqoom dilemma just yet...
But maybe we can petition Skin Essential Actives and see if they'll carry it for us? |
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302 (Part one): http://www.essentialdayspa.com/forum/viewthread.php?tid=28855&postdays=0&postorder=asc&&start=0 |
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Thu Sep 12, 2013 7:34 pm |
| fawnie wrote: |
| Daler, from Evonik. |
thank u fawnie.. can I ask what's their minimum purchase requirements( quantity) just in case you know... TIA! |
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Thu Sep 12, 2013 8:25 pm |
| Lowbrowscientist wrote: |
| fawnie wrote: |
| Daler, from Evonik. |
Fawnie!! You might have just solved the Sqoom gel dilemma!
(By the way, I've looked over your website and your products look lovely! Maybe you can formulate a nice, affordable version of the Sqoom gels for us?)
Edited to add: Evonik requires you to register with a company name, and they probably have a required minimum purchase, so I guess it remains to be seen if we've solved the Sqoom dilemma just yet...
But maybe we can petition Skin Essential Actives and see if they'll carry it for us? |
Fawnie does make very nice products. And I would personally prefer that she make up something or carry it for us rather than have to deal with someone else. |
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No longer answering PM's due to numerous weird messages. |
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Fri Sep 13, 2013 2:27 am |
| fawnie wrote: |
Thank you light123, v interesting.
This article suggests that HA of 50 kDa is not pro-inflammatory, but its supported by the company Evonik which mfr's HA:
Fifty-kDa Hyaluronic Acid Upregulates Some
Epidermal Genes without Changing TNF-
Expression in Reconstituted Epidermis
Ive used 50 weight HA and found it v nice for plumping up lines. Long term? dunno yet. |
Hi Fawnie, First I was excited by the results of this article, until read more on the topic i found out that knowing TNF-alpha are not activate is good but definitely not enough when looking at the inflammation cascade. TNF are related to keratinocytes, the skin extracellular matrix degradation is induced by other factors, which are not covered in this study.
No doubt LMW HA works well on plumping the skin, I just would like to be sure i will not deplete the thickness of my skin.
jimmunol(dot)org(backslash)content/177/2/1272.long |
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52 years, sagging sucks |
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Fri Sep 13, 2013 7:35 am |
Yes, its a puzzle what to use really. And its not just one magic bullet it has to be a combination of ingredients and devices and exercise and diet and massage, etc etc to forestall the ravages.
So you would *not* use HA50 KDa, light123? (or any HA for that matter?)
Daler to answer your Q about pricing, this is the most recent quote:
Product Name: Hyacare 50
INCI Name: Hydrolyzed Hyaluronic Acid
Manufacturer: Evonik
Packaging: 0.5kg containers
MOQ: 0.5kg
Pricing: $3,732.04/kg (delivered)
FOB: Hopewell, VA
Bearing in mind only 1% is needed, thats a lot of HA serum. |
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✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Fri Sep 13, 2013 7:43 am |
| Lowbrowscientist wrote: |
(By the way, I've looked over your website and your products look lovely! Maybe you can formulate a nice, affordable version of the Sqoom gels for us?) |
Thnx scientist, Im sure I could, but I dont like to use aloe vera which is in the Sqoom gels IIRC. |
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✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Fri Sep 13, 2013 8:05 am |
| fawnie wrote: |
| Lowbrowscientist wrote: |
(By the way, I've looked over your website and your products look lovely! Maybe you can formulate a nice, affordable version of the Sqoom gels for us?) |
Thnx scientist, Im sure I could, but I dont like to use aloe vera which is in the Sqoom gels IIRC. |
Fawnie, what would you use instead? |
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No longer answering PM's due to numerous weird messages. |
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Fri Sep 13, 2013 10:14 am |
| fawnie wrote: |
Daler to answer your Q about pricing, this is the most recent quote:
Product Name: Hyacare 50
INCI Name: Hydrolyzed Hyaluronic Acid
Manufacturer: Evonik
Packaging: 0.5kg containers
MOQ: 0.5kg
Pricing: $3,732.04/kg (delivered)
FOB: Hopewell, VA
Bearing in mind only 1% is needed, thats a lot of HA serum. |
oyeee
that's a lot of $$$ too!
but thank u very much for this info fawnie. |
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Fri Sep 13, 2013 11:51 am |
| so now that I know this ridiculous price of 50 K dalton HA, I am doubting that study, I think the study was done by the same company, Evonik, right? This HA is way way overpriced.. from lotioncrafters you can get either form of HA ( not 50 k dalton though) for $900 to $1000 per KG! Evonik is selling it for almost $3000 more.. now it cant cost em that much to degrade HA to 50 K dalton, something is fishy here. |
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Fri Sep 13, 2013 2:16 pm |
Yes, as stated in the study, Evonik funded it.
I still would rather use the 50 KDa one than whatever LC is selling tho. Regardless of the price. *shrug* personal preference: when you DIY *for* yourself you can use whatever pleases you!
Bethany, I have other things I use instead of aloe vera. |
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✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Fri Sep 13, 2013 2:31 pm |
| fawnie wrote: |
Yes, as stated in the study, Evonik funded it.
I still would rather use the 50 KDa one than whatever LC is selling tho. Regardless of the price. *shrug* personal preference: when you DIY *for* yourself you can use whatever pleases you!
Bethany, I have other things I use instead of aloe vera. |
but DIYer dont have $3750 to spend on HA!!! lol.. at least not me. |
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Fri Sep 13, 2013 3:20 pm |
Thats the price per kg, daler. MOQ is 0.5kg. Better?  |
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✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Fri Sep 13, 2013 5:03 pm |
| fawnie wrote: |
| Thats the price per kg, daler. MOQ is 0.5kg. Better? |
phew.. now that's doable  |
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Fri Sep 13, 2013 5:07 pm |
| Thought so! ROFL |
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✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Sat Sep 14, 2013 8:27 am |
| fawnie wrote: |
| Thats the price per kg, daler. MOQ is 0.5kg. Better? |
I think I'm missing something...isn't that still $1875? 0.5kg = half a kg. Not sure I would ever use that much. |
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Sat Sep 14, 2013 10:54 am |
| ShastaGirl wrote: |
| fawnie wrote: |
| Thats the price per kg, daler. MOQ is 0.5kg. Better? |
I think I'm missing something...isn't that still $1875? 0.5kg = half a kg. Not sure I would ever use that much. |
u missed the intended pun  |
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Sat Sep 14, 2013 12:12 pm |
I tried Ebay and one supplier came up selling 50 kDa HA for an absolutely reasonable price, 10g for 18$. Sorry, not allowed to place the link here.
I would like to buy actually HA with MW above 500 kDa, does anybody know where I can get such?
Jus discovered that I am restricted to post often  , well, time goes fast 
Hope it helps,
Nora |
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52 years, sagging sucks |
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Sat Sep 14, 2013 1:32 pm |
| light123 wrote: |
I tried Ebay and one supplier came up selling 50 kDa HA for an absolutely reasonable price, 10g for 18$. Sorry, not allowed to place the link here.
I would like to buy actually HA with MW above 500 kDa, does anybody know where I can get such?
Jus discovered that I am restricted to post often , well, time goes fast
Hope it helps,
Nora |
you can buy it from lotioncrafters ( they sell 3 kinds) so buy the regular one... or skinessentialactives or skinactives or bulkactives |
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Sat Sep 14, 2013 2:25 pm |
Daler, thanks, I checked. Skin essentials sell 1,000 kDa HA, others DO NOT provide that info on product page, so hard to guess.
Fascinating, just went through a study showing that if there are fragments of 500 Kda HA around, fibroblasts happily synthesy new HA, if the fragments are shorter, nothing happen 
As said, I bought 10 kDa HA from Skin Essentials mainly due to the info there, when I asked for supporting articles or publications, I got a nice response "don't use it if you have any doubts".
So, I have a sealed bottle of this stuff that i don't know what to do with.
Anyhow, now i am searching 500-800 kDA HA,who sells such?
Cheers,
Nora |
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52 years, sagging sucks |
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Sat Sep 21, 2013 11:15 am |
| Lotusesther wrote: |
Well I have ordered a gadget ultrasound thingy and LW HA. Both items are on their way here and I hope they will be here in time for my 52nd birthday next month.
Hopefully this will do something nice, I'll report back after using it for a while. Fingers crossed it will work! |
Hi Lotus, did you try the LMW HA? Do you see any effect?
Would be nice to learn from your experience.
Light |
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52 years, sagging sucks |
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Wed Oct 02, 2013 8:36 pm |
So what's the verdict on the LMW-HA? Any *filler faces* out there yet..  |
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♥I'm flattered by all the lovely PM's, but I don't get here much these days. Please don't be afraid to post your quearies to other DIY members who will be glad to help you (or sell you their wares..lol) Still happy with LED, dermarolling and a DIY antioxidant regime. Peace & Hugs to all.♥ |
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