Retinyl acetate
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free skin care · Fri Jan 23, 2009 7:48 pm

I just received my latest order from Skinactives and amongst other things I had ordered Retinyl acetate on a whim. I'd forgotten all about it until it arrived, and now I'm having a really hard time finding information about the active and about how effective it is. Confused

Here's what it says on the Skinactives website: Retinyl Acetate and other retinoids are used as antiaging chemicals. Vitamin A is absorbed through the skin and increases the rate of skin turnover, and gives an increase in collagen resulting in a more youthful appearance.

I'm already using Skinceuticals 1% retinol on my face, so I was planning on doing what is suggested on the site and mixing 2.4gm into 4oz of base cream for an antiaging bodylotion.

Since I don't know how strong retinyl acetate is compared to retinol and retinyl palmitate, I'm just wondering if anyone has any experience using it? Most importantly, does it work? Laughing

Also, should I use it on it's own or can I mix it with other actives? I do have matrixyl 3000 and Q10 as well.
Thanks in advance. Smile

free skin care · Sun Jan 25, 2009 11:40 am

Hi, Magica.
I am sorry I don't have an answer to your question. I would assume that retinyl acetate is considerably less potent than retinol, but that's it.

Just wanted to say that I think it's a great idea to add active ingredients to a base cream and use it as a body lotion. I am planning on making a body lotion by adding 5 % niacinamide to the base cream from Skinactives. Smile

free skin care · Sun Jan 25, 2009 1:44 pm

Sounds great. Good luck with your body lotionmaking endeavours. Very Happy

Yes, retinyl acetate is probably a lot less potent, but I'm sure it will still do some good. Smile

free skin care · Sat Apr 10, 2010 2:45 am

Hi everyone,

I know this quite an old post, but I was wondering if anyone has anything to report of retinyl acetate usage ?

thanks

Jackie xx

Wed Feb 02, 2011 10:24 pm

"...retinyl acetate was about half as effective as the retinoic acid and that the retinyl palmitate was only half as effective as retinyl acetate in producing remediative effects on photo damaged skin."

free skin care · Mon Apr 11, 2011 6:32 pm

Hi, I know I'm bumping up an old post but why create a new one when this exists? Very Happy

Anyway, I wonder if anyone has any more information on retinyl acetate? From what I can read online, it says it's basically a synthetic version of retinyl palminate. But if that's true wouldn't it be the same strength? The post above mine makes it seem as though it's the same strength as retinol.

The above post has no source cited so I was wondering if anyone knew?

I have a cream that is .3% retinyl acetate and I've been using it nightly on sensitive skin and I notice no redness, peeling, itching, or any negative side effects so I wonder if it's actually working. TIA!

free skin care · Tue Apr 12, 2011 2:02 pm

http://www.ncbi.nlm.nih.gov/pubmed/7561157

http://www.fda.gov.tw/files/publish_periodical/10-4-8.PDF

http://journal.scconline.org/pdf/cc1988/cc039n04/p00235-p00240.pdf

Jarrett A, Wrench R, Mahmoud B. The effects of retinyl acetate on epidermal proliferation and differentiation. I. Induced enzyme reactions in the epidermis. Clin Exp Dermatol1978; 3:173188.2.
Spearman RI, Jarrett A. Biological comparison of isomers and chemical forms of vitaminA (retinol). Br J Dermatol 1974; 90:553560.3.
Shuster S, Black MM, McVitie E. The influence of age and sex on skin thickness, skin collagen and density. Br J Derm 1975; 93:639¿643.4.
Courts DF, Skreko F, McBee J. The effect of retinyl palmitate on skin composition and morphometry.J Soc Cosmet Chem 1988; 39:235240.5.
Fthenakis CG, Maes DH, Smith WP. In vivo assessment of skin elasticity using ballistometry.J Soc Cosmet Chem 1991; 42:211 222.

Doesn't have to irritate to be helpful.

free skin care · Tue Apr 12, 2011 2:33 pm

Thanks DragonN but none of those articles discuss retinyl acetate.

I know retinol works and I know what retinyl palmitate does in comparison with retinol and retinoic acid.

But I was looking for information on retinyl acetate and how it compares to palmitate or retinol.

Thanks.

free skin care · Tue Apr 12, 2011 6:09 pm

Retinyl palmitate is a synthetic alternate for retinyl acetate in vitamin A supplements, and is available in oily or dry forms. It is a common vitamin supplement, available in both oral and injectable forms for treatment of vitamin A deficiency, under the brand names Aquasol A, Palmitate A and many others. It is a pre-formed version of vitamin A; therefore, the intake should not exceed the Recommended Dietary Allowance (RDA). Overdosing preformed Vitamin A forms such as retinyl palmitate leads to adverse physiological reactions (hypervitaminosis).

http://en.wikipedia.org/wiki/Retinyl_palmitate

free skin care · Tue Apr 12, 2011 8:50 pm

Hannah at skinactives uses retinyl acetate and not retinyl palmitate, there must be a good reason for it!

free skin care · Wed Apr 13, 2011 10:30 am

daler wrote:

Hannah at skinactives uses retinyl acetate and not retinyl palmitate, there must be a good reason for it!

Oh, good to know! I know there are some studies now saying that retinyl palmitate may be carcinogenic in lab mice. Shock

Thank you Daler and DarkMoon!

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