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Topical Niacinamide
EDS Skin Care Forums Forum Index » Skincare Tools & Do-It-Yourself Skincare
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beaverbuzz
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Mon Apr 18, 2011 4:05 pm      Reply with quote
Hi Everyone,

First time poster, but long time reader.

I recently purchased some creams from Skin Actives. I also have in my possession some Niacinamide and N-Acetyl-D Glucosamine that I wish to add to the creams.

My first question is: can I just add both powder/crystals to the cream and stir them in ? Is that all that is required?

My second question: I don't have a scale that can measure mg and I don't know exactly how much to put in say a 4Oz Skin active cream?

Any help would be appreciated, thank you so much!

BB
daler
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Mon Apr 18, 2011 8:12 pm      Reply with quote
A teaspoon of each in 4 oz would be fine; and yes you can simply add em and mix well or you can dissolve each, separately , in small amount of water first and then add.
DragoN
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Wed Apr 20, 2011 11:38 pm      Reply with quote
BB

B3 and NAG is a lovely combination, both water soluble and easy to work with. How much cream? And what percentage use are you looking at?

You can save yourself a great deal of grief and appreciate far greater benefit of your actives when using them at the correct percentages. It's easy and cheap to do with a decent scale. Makes DIY a real cinch to create potent potions.

I personally absolutely loathe tsp measurements of actives...they have different densities and is a most inaccurate measurement. When working with actives, accuracy does matter. It makes a huge difference in their effect.

It's your skin and your right to do as you please with it.
Ava with wings
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Sat Apr 23, 2011 9:53 am      Reply with quote
Please excuse my ignorance... Niacinamide is B3.. But what does it do?

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Late 30's, fair skin, dark hair. Retin A, DIY potions. Missions completed- acne, acne scarring, 11's, redness, contact dermatitis. Working on maintenence and cellulite.
oasisjc
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Sat Apr 23, 2011 10:47 am      Reply with quote
Ava with wings wrote:
Please excuse my ignorance... Niacinamide is B3.. But what does it do?


It mostly helps to dilate your blood vessels so that more nutrients and oxygen can be perfused into your skin more easily. It also has some flushing effects too due to the increased blood flow.
DragoN
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Sun Apr 24, 2011 9:30 am      Reply with quote
....does quite a bit more than that^^

Niacinamide has been extensively studied and proven to increase the rate of collagen synthesis, lighten and even skin tone, reduce and eliminate acne as well as improve the skin's own production of Hyaluronic acid. Niacinamide also reduces sebum production thereby reducing the appearance of pore size. [ effective at 2% in clinical trails ]

Niacimamide aids in the increase of ceramide production in the skin and improves skin barrier function. TEWL [ trans epidermal water loss ] is reduced. Vitamin B3 has also been shown to increase the production of NADPH in older skin to that of levels as once produced in youth.

DNA is the rare biomolecule that is not discarded when it is damaged, but rather is repaired. Human cells have developed two fundamental repair strategies to restore DNA to its native sequence and conformation.

More than 20 different proteins participate in this multistep process, and many of these proteins also participate in RNA transcription and/or DNA synthesis. The process of DNA repaid relies on the presence of Nicotinamide adenine dinucleotide {NAD} which is rapidly depleted during the repair process. Niacinamide is member of the the vitamin B family and is crucial that it is in reserve for dermal cells to replenish NAD.

Tanno O, Ota Y, Kitamura N, Katsube T, Inoue S. Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. B J Dermatol 2000; 143:525¿531.

Gensler HL. Prevention of photoimmunesuppression and photocarcinogenesis by topical niacinamide. Nutr Cancer 1997; 29:157-162.

Yu J-M, Liu Y, Xie N, Sun W, Wang J-J, Li H-Q. Effects of nicotinamide on levels of dermis hydroxyproline in photoaging skin. Huanjing Yu Jiankang Zazhi 2002; 19:102-104.

Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DK. Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. Int J Dermatol 1995; 34:434-437.

Girffiths CEM. Nicotinamide 4% gel for the treatment of inflammatory acne vulgaris. J Dermatol Treat 1995; 6:S8¿S10.
NotMeNotYou
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Tue Apr 26, 2011 6:38 pm      Reply with quote
I'll vouch for getting a scale, 5gms of niacinamide is a lot more than a tsp. Most clinical studies on this active use it in either 2% in conjunction with something else or 5% on its own. You cant hope to formulate with the correct amount using cooking measures.

I've been using niacinamide on my skin daily for the past 3 weeks, no dramatic changes yet but my skin is a lot smoother and less prone to dryness. Hydration has definately been improved. That alone can shave 5yrs off your appearance.

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butterfliesandflowers
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Mon May 30, 2011 7:39 am      Reply with quote
Hi everyone Laughing
Just wondered if I'm making my own nia serum, does it need to be kept in the fridge. Also is it prone to going off quickly like vit c serum is or is it a bit more robust than that, thanks!
paulspnao
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Tue May 31, 2011 4:58 am      Reply with quote
Nice post. It mostly helps to dilate your blood vessels so that more nutrients and oxygen can be perfused into your skin more easily. It also has some flushing effects too due to the increased blood flow. I've been using niacin amide on my skin daily for the past 3 weeks, no dramatic changes yet but my skin is a lot smoother and less prone to dryness. Hydration has definitely been improved. That alone can shave 5yrs off your appearance. Thanks for sharing..
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