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Fri Jun 08, 2012 10:39 pm  |
| Hi Ladies - Have any of you tried Raspberry Ketones? Dr. Oz raved about them to shrink fat cells. Thinking of trying them and wondering if anyone had any success? |
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Sat Jun 09, 2012 11:51 am |
According to Dr Oz. A tad premature to rave IMO.
"What did scientists do in the lab?
In one experiment, to test the effect on obesity, mice were fed a high-fat diet plus raspberry ketone for about 10 weeks. Other experiments were carried out in vitro (in test tubes, petri dishes, etc.).
What did scientists learn about fat cells?
Researchers observed that, compared to controls, raspberry ketone decreased the amount of fat in the liver and visceral adipose (abdominal fat) tissues of mice. It also significantly increased norepinephrine-induced lipolysis (the decomposition of fat) in some rat fat cells.
Researchers also tested in vitro fat cells with raspberry ketone and found that they showed greater evidence of breakdown when compared to controls.
What did scientists conclude?
They concluded that raspberry ketone prevents and improves obesity and fatty liver in certain animal models. While the exact mechanism has not been thoroughly understood, these effects appear to stem from the action of raspberry ketone in altering the lipid metabolism, or more specifically, in increasing norepinephrine-induced lipolysis in white adipocytes (fat cells).
Scientists speculate that raspberry ketone stimulates the energy metabolism via a mechanism similar to that of capsaicin. Capsaicin, a compound found in chili peppers, has been looked at in humans for weight loss.
In another study, the effect of raspberry ketone on energy metabolism was examined by measuring metabolic markers in brown fat tissue, a special kind of fat that generates heat in a process called thermogenesis. These results reportedly indicate that raspberry ketone activates the brown fat thermogenesis and enhances energy metabolism. In any case, more detailed studies are called for to determine a mechanism for raspberry ketone.
What do the animal data on raspberry ketone mean for humans?
Mice and rats are the most widely used animal models in biomedical research. It is important to note that besides being non-human mammals, these animals are housed under standard laboratory conditions, and the use of overweight and unstimulated animals as standard controls may bias the measured experimental outcomes.
Animal models and test tube experiments are important parts of scientific discovery and innovation, especially at early stages. Positive early results in the lab can be promising, but these do not always mean the same outcomes will occur in humans.
References
Koeduka T, Watanabe B, Suzuki S, Hiratake J, Mano J, Yazaki K. Characterization of raspberry ketone/zingerone synthase, catalyzing the alpha, beta-hydrogenation of phenylbutenones in raspberry fruits. Biochem Biophys Res Commun. 2011;412(1):104-8.
Tateiwa J I, Horiuchi H, Hashimoto K, Yamauchi T, Uemura S. Cation-exchanged montmorillonite-catalyzed facile Friedel-crafts alkylation of hydroxy and methoxy aromatics with 4-hydroxybutan-2-one to produce raspberry ketone and some pharmaceutically active compounds. J Org Chem 1994; 59: 5901-5904.
Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, Okuda H. Anti-obese action of raspberry ketone. Life Sci. 2005;77(2):194-204."
http://www.doctoroz.com/videos/rasberry-ketone-what-science-says |
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Sensitivity, forehead pigmentation & elevens, nose & chin clogged pores. Topicals: Aloe vera, squalane, lactic acid, Myfawnie KinNiaNag HG: Weleda calendula, Lanolips, Guinot masque essentiel, Flexitol Naturals, Careprost. Gadgets: Vaughter dermarollers, Lightstim. |
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Sat Jun 09, 2012 5:56 pm |
Dr Oz is a media pumper.
BFG |
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Sat Jun 09, 2012 6:38 pm |
| I've tried it~I bought some( in the "powder" form (more like the texture of sugar) from Amazon- less expensive and doesn't have other additives. It does cut my appetite: I just pour a little in my hand and take with water. It smell like raspberry but has a very bitter taste. I started out by adding it to a little juice. Dr. Oz does promote way too many items, but this is one I'm glad I decided to check out. |
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Sat Jun 09, 2012 10:39 pm |
| Barefootgirl wrote: |
Dr Oz is a media pumper.
BFG |
very true.. btw, is he still out spoken about not consuming high fructose corn syrup or did the industry lobbyists get to him? |
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Sun Jun 10, 2012 11:15 am |
| angelfire what are your results so far? do you notice a decrease in fat cells? my worry is that while it would be great to shrink up some fat on my butt and thighs, that it would shrink all my fat cells including in my face and make me look gaunt. Let me know your results - I am so close to giving it a try! |
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