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Sun Nov 04, 2012 1:51 pm  |
What do you think of resveratrol?
It's purported to be one of the most effective anti-aging supplements. From your experience, have you found it to be as effective as it's reputed to be?
Also, what is your opinion of other anti-aging supplements, such alpha-lipoic acid, coenzyme Q10, and grape seed extract? |
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Mon Nov 05, 2012 12:42 pm |
Don't Be Conned By the Resveratrol Scam by Ray Peat:
http://www.functionalps.com/blog/2011/04/26/don%E2%80%99t-be-conned-by-the-resveratrol-scam/
Part of the cultural framework that makes it easy to sell that idea is the old “rate of living” theory of aging, the idea that we have only so many heartbeats in a lifetime, that we can use only so many calories and so much oxygen in a lifetime, and that organisms with a low metabolic rate therefore live longer than those with a high metabolic rate. The rate of living theory is closely related to the “wear and tear” theory of aging, that our bodies are (except for our germ cells) made up of “post-mitotic cells,” unable to continue dividing once growth is complete, and so must die when those cells are “worn out.” By the middle of the 20th century, those ideas had been disproved in many ways, but in the 1960s Leonard Hayflick renewed for a time the doctrine of aging as the wearing out of unrenewable cells, with his doctrine that somatic cells (non-germ cells) have an absolute limit of 50 replications. Producing cloned animals from somatic cells, and the subsequent excitement about stem cells, made that theory obsolete (again). |
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Mon Nov 05, 2012 9:11 pm |
There is some interesting information and studies on the Sloan Kettering site
http://www.mskcc.org/cancer-care/herb/resveratrol
The original research that got so much attention was done on resveratrol derived from muscadine grapes. Many if not most of the products available on the market now come from the much cheaper Japanese knotwood. |
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Tue Nov 06, 2012 8:52 am |
My heart doctor encourages it along with Omega,calcium and a multi-vitamin for me. His skin looks amazing!!!!
I have taken it several times in the past and I do like products with it. |
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Joined the 50 club several years back, blonde w/ fair/sensitive skin, Texas humidity and prone to rosacea, light breakouts and sunburns, combo skin type, starting to see sundamage and fine lines |
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Tue Nov 06, 2012 10:31 am |
Dr. James Johnson recommends resveratrol. What a slowed metabolism looks like:
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Tue Nov 06, 2012 12:28 pm |
| Wow. Okay, on another note I had a sample of Caudalie that contained it and I really liked it. |
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Joined the 50 club several years back, blonde w/ fair/sensitive skin, Texas humidity and prone to rosacea, light breakouts and sunburns, combo skin type, starting to see sundamage and fine lines |
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Tue Nov 06, 2012 12:47 pm |
| AnnieR wrote: |
My heart doctor encourages it along with Omega,calcium and a multi-vitamin for me. His skin looks amazing!!!!
I have taken it several times in the past and I do like products with it. |
I wonder how many MGs a person would have to take a day to see positive change? |
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Tue Nov 06, 2012 2:40 pm |
I like PubMed for studies:
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| After 60 days of treatment, values for systemic oxidative stress, plasmatic antioxidant capacity, and skin antioxidant power had increased significantly. Additionally, skin moisturization and elasticity had improved, while skin roughness and depth of wrinkles had diminished. Intensity of age spots had significantly decreased, as evidenced by improvement in the individual typological angle. |
Source: http://www.ncbi.nlm.nih.gov/pubmed/23071399
However, in another study, resveratrol supplementation in post-menopausal non-obese women did not have a positive effect on their metabolism:
http://www.ncbi.nlm.nih.gov/pubmed/23102619
So, good as antioxidant  |
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Female, born 1985. HW Engineer, Fitness nut. Embarking on the war against the signs of aging... |
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Sun Dec 23, 2012 10:15 am |
| The punchline for resveratrol at the moment--to be more rigorously confirmed--is that it seems to be effective for those with metabolic syndrome (diabetic symptoms, cardiovascular disease, etc.), but not for regular healthy people (i.e., waste of money if you are healthy). This is also born out by a review of experiments in rodents, in which it helped diabetic rodents but did nothing for normal healthy rodents. If you do decide to supplement with it, aim for 150+ mg/day of 99+% pure trans-resveratrol (e.g., ResVida). Other formulations may not be so pure, so be aware that this will affect the dosage. I don't personally take it myself, just am knowledgeable in this area. |
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34 y.o. FlexEffect and massage. Love experimenting with DIY and botanical skin care products. Appreciate both hard science and natural approaches. Eat green smoothies + lots of raw fruit and veggies. |
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