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obagi hydroquinone safety & compatible alternatives
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SoMaYVR
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Mon Oct 08, 2012 9:54 am      Reply with quote
does anybody know if using Obagi indefinitely is unsafe?

i'm wondering if Obagi is the type of skincare that one should stop using after it has cleared up one's skin condition.

my concern is using hydroquinone for years may be bad for one's health.

does it have side effects?
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Wed Oct 10, 2012 6:04 am      Reply with quote
It is my understanding that 2% can be used more often but 4% should only be used for 3 months at a time, wait 3 months, re-start...rinse and repeat. There are some concerns that it can cause cancer (but it sounds like you must eat it and eat lots and lots of it) and is banned in some countries.

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Thu Oct 11, 2012 7:00 pm      Reply with quote
There are also concerns that hq can cause ochronosis, which is a disfiguring skin condition.
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Sat Oct 13, 2012 6:29 am      Reply with quote
Well, once your skin has cleared up, Obagi suggested that you continue with "maintenance" and still use the product to maintain the results. If you don't, the skin will revert back to where it was.

If you are concern with hydroquinone, then I suggest you use Obagi Nu-derm FX clear which is similar to Obagi Nu-derm clear, except it does not contain nydroquinone at all. This is your best bet.

SoMaYVR wrote:
does anybody know if using Obagi indefinitely is unsafe?
i'm wondering if Obagi is the type of skincare that one should stop using after it has cleared up one's skin condition.
my concern is using hydroquinone for years may be bad for one's health.

jade-1234
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Mon Oct 15, 2012 8:07 pm      Reply with quote
Hello ZOSKIN Smile I don't think EDS sells Brightenex, so where do you suggest to buy this product with your recommendation aside from the doctor's office? Will EDS sells it? Why or why not?

Also, what is the main ingredients of Brightenex that will even out or lighten skin tones?

ZOSKIN wrote:
I work at ZO SKIN HEALTH Inc. In 2012 we introduced Dr. Zein Obagi's newest creation of comprehensive skin health solutions, ZO Medical products; sold exclusively in physicians offices.

I work very closely with Dr. Obagi on new product development and I can confirm that he no longer recommends continuous use of HQ. (No more that 3-5 months) He has seen patients in his practice with severe skin pigmentation problems due to prolonged use of HQ. He developed a new non-hydroquinone product called BRIGHTENEX to address pigmentation issues. It is safe and ideal for maintenance after HQ therapy. Note: Dr Obagi is no longer affiliated with Obagi Medical Products.
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Tue Oct 16, 2012 10:50 am      Reply with quote
I would also really love to know how I can go about purchasing Brightenex. I have had great success on the Nu Derm system, and am about to go on maintenance, and would really like to use as little hydroquinone as possible.

I'm in Vancouver, Canada, and have called several clinics who carry the Zo line, but none of them carry Brightenex. Also, I noticed Zo Medical carries two 4% hydroquinone products; Melamix & Melamin. Does Dr. Obagi limit use of these products to strictly 3-5 months, and then suggest Brightenex to maintain the HQ results, with absolutely no HQ involved for maintenace? And in your experience has Brightenex (coupled with diligent use of strong broad spectrum ss) been successful at maintaining HQ results for those with stubborn pigmentation issues (melasma) like myself.

Sorry for all the questions! I am just so happy with my Nu Derm results, and am very anxious about finding the most effective and safest way to go about maintaining them! Any suggestion on how to purchase Brightenex would be greatly appreciated!



jade-1234 wrote:
Hello ZOSKIN Smile I don't think EDS sells Brightenex, so where do you suggest to buy this product with your recommendation aside from the doctor's office? Will EDS sells it? Why or why not?

Also, what is the main ingredients of Brightenex that will even out or lighten skin tones?

ZOSKIN wrote:
I work at ZO SKIN HEALTH Inc. In 2012 we introduced Dr. Zein Obagi's newest creation of comprehensive skin health solutions, ZO Medical products; sold exclusively in physicians offices.

I work very closely with Dr. Obagi on new product development and I can confirm that he no longer recommends continuous use of HQ. (No more that 3-5 months) He has seen patients in his practice with severe skin pigmentation problems due to prolonged use of HQ. He developed a new non-hydroquinone product called BRIGHTENEX to address pigmentation issues. It is safe and ideal for maintenance after HQ therapy. Note: Dr Obagi is no longer affiliated with Obagi Medical Products.
denisiel
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Fri Oct 26, 2012 9:10 pm      Reply with quote
This thread is so timely for me as I just went on maintenance 2 weeks ago after 24 weeks of aggressive Nuderm regime. Some of the pigmentation has already come back even though I wear sunscreen indoors and outdoors and reapply every two hours. I use Clear 3X a week and Skinoren (azelaic acid for pigmentation)the other days, tretinoin .1% every day and mixed with Blender 3 x a week.

Now I am worried that if Dr. Obagi doesn't recommend hydroquinone use after Nuderm then what can keep the pigmentation from returning? Kojic acid, azelaic acid and arbutin don't wipe out the brown areas, they just lessen the effect.

On non-Nuderm days I am also using ZO Skin Health Growth Factor Serum and the Ommerse Day & Night Creams. Use Vitamin C serum daily

The ingredients of Brightenex are retinol (which I am already getting via the ZO Skin Health products listed above and in the tretinoin) and vitamin C.

The only ingredients that may be different than in Nuderm and ZO Skin Health are the "Multistage glutathione, soy isoflavones, and N-acetyl glucosamine melanin inhibitor system". Does anyone know what exactly that comprises. The Obagi products are so pricey and I don't want to duplicate products.

If anyone has successfully done the NuDerm regime and has been able to keep melasma from returning without using hydroquinone, I would greatly appreciate if you would post your routine with products! Many thanks to all you ladies!
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Sat Oct 27, 2012 9:42 am      Reply with quote
I also anxious for a reply from one of our new forum member, ZOSKIN..... regarding Brightenex.....
blanchedubois
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Mon Oct 29, 2012 4:34 pm      Reply with quote
jade-1234 wrote:
I also anxious for a reply from one of our new forum member, ZOSKIN..... regarding Brightenex.....


As am I! ...

denisiel, I am so glad you posted! Sounds like we are at similar stages in our Nu Derm journey Smile I also started the program because of persistent melasma, and have had really amazing results so far but I have this terrible fear of it all returning when I go onto maintenance... which I am almost ready to begin. I have to admit, I am discouraged that you have seen some pigmentation return after only 2 weeks, and you sound like you are doing everything right! You're even using an alternate melanin inhibitor (skinoren) which is exactly what I planned to do on maintenace... What kind of sunscreen are you using? One thing I have learned is that when it comes to melasma a very effective physical sunscreen with a high zinc content is sooo important. Is your sunscreen physical or chemical? Do you live in a place that gets a lot of sun year round?
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Mon Oct 29, 2012 7:39 pm      Reply with quote
blanchedubois wrote:
denisiel, I am so glad you posted! Sounds like we are at similar stages in our Nu Derm journey Smile I also started the program because of persistent melasma, and have had really amazing results so far but I have this terrible fear of it all returning when I go onto maintenance... which I am almost ready to begin. I have to admit, I am discouraged that you have seen some pigmentation return after only 2 weeks, and you sound like you are doing everything right! You're even using an alternate melanin inhibitor (skinoren) which is exactly what I planned to do on maintenace... What kind of sunscreen are you using? One thing I have learned is that when it comes to melasma a very effective physical sunscreen with a high zinc content is sooo important. Is your sunscreen physical or chemical? Do you live in a place that gets a lot of sun year round?


Hi blanchedubois, nice to have someone also going on maintenance and who is using Nuderm for melasma - we can share knowledge!

I am now using Clear 3 x week both AM and PM even though Obagi says use PM only. Using Skinoren (20% azelaic acid) on the other days, also both AM & PM. I dropped Exfoderm (mainly because I left it at a hotel) but am trying the PTR Peel Pads and Mangosteen Peeling Gel for exfoliation along with microfiber cloths. Skinceuticals C & E Ferulic daily. Using 1/2 gram of Blender and .1% tretinoin cream on the Nuderm nights and just tretinoin on non-Nuderm nights.

I was really hoping that the schedule would get sped up once on maintenance. Still takes a long time due to wait times between products but I want to give everything the full chance to work.

I live in California and Hong Kong, which are both sunny places and I do a lot of outdoor activities. BUT I always wear a hat and carry a UV umbrella (at least in HK where this is socially acceptable). Plus I even wear a UV mask along with a hat and neck gaitor when in HK when biking or sailing.

Underneath all this garb, I wear Skinceuticals Ultimate UV Defense SPF 30, which is a mix of chemical and physical sunscreen. After letting it absorb, I layer on Suntegrity 5 in 1 sunscreen SPF 30, which is 20% Zinc Oxide. For foundation, I use a mineral powder with sunscreen, such as Laura Mercier SPF15, Physician Formula Healthy Wear SPF50 or Jane Iredale SPF20. Throughout the day I touch up with PTR powder sunscreen SPF30. I use it indoors and out. So there is just no way I am getting melasma from exposed skin!

Two brown patches are coming back and I can see them under foundation, which is such a disappointment after enduring 24 weeks of nonstop peeling and redness.

I don't understand how member ZOSKIN can say that Dr. Obagi no longer recommends long term hydroquinone use. Even on the ZO Skin website blog, Dr. Obagi often recommends to use Nuderm and then his products on non-Nuderm days. He always says you can never go off Nuderm (which I take means using hydroquinone) if you have melasma.

I had already used .1% tretinoin and Skinoren for a year before Nuderm and that combo removed 50% of the melasma. I am only trying to limit hydroquinone use because it plateaus and becomes ineffective long term. But now I have no idea what to do to keep the melasma from coming back fully. I don't want to be on the full NuDerm regime because that will also lose efficacy over time.
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Mon Oct 29, 2012 8:39 pm      Reply with quote
denisiel wrote:
blanchedubois wrote:
denisiel, I am so glad you posted! Sounds like we are at similar stages in our Nu Derm journey Smile I also started the program because of persistent melasma, and have had really amazing results so far but I have this terrible fear of it all returning when I go onto maintenance... which I am almost ready to begin. I have to admit, I am discouraged that you have seen some pigmentation return after only 2 weeks, and you sound like you are doing everything right! You're even using an alternate melanin inhibitor (skinoren) which is exactly what I planned to do on maintenace... What kind of sunscreen are you using? One thing I have learned is that when it comes to melasma a very effective physical sunscreen with a high zinc content is sooo important. Is your sunscreen physical or chemical? Do you live in a place that gets a lot of sun year round?


Hi blanchedubois, nice to have someone also going on maintenance and who is using Nuderm for melasma - we can share knowledge!

I am now using Clear 3 x week both AM and PM even though Obagi says use PM only. Using Skinoren (20% azelaic acid) on the other days, also both AM & PM. I dropped Exfoderm (mainly because I left it at a hotel) but am trying the PTR Peel Pads and Mangosteen Peeling Gel for exfoliation along with microfiber cloths. Skinceuticals C & E Ferulic daily. Using 1/2 gram of Blender and .1% tretinoin cream on the Nuderm nights and just tretinoin on non-Nuderm nights.

I was really hoping that the schedule would get sped up once on maintenance. Still takes a long time due to wait times between products but I want to give everything the full chance to work.

I live in California and Hong Kong, which are both sunny places and I do a lot of outdoor activities. BUT I always wear a hat and carry a UV umbrella (at least in HK where this is socially acceptable). Plus I even wear a UV mask along with a hat and neck gaitor when in HK when biking or sailing.

Underneath all this garb, I wear Skinceuticals Ultimate UV Defense SPF 30, which is a mix of chemical and physical sunscreen. After letting it absorb, I layer on Suntegrity 5 in 1 sunscreen SPF 30, which is 20% Zinc Oxide. For foundation, I use a mineral powder with sunscreen, such as Laura Mercier SPF15, Physician Formula Healthy Wear SPF50 or Jane Iredale SPF20. Throughout the day I touch up with PTR powder sunscreen SPF30. I use it indoors and out. So there is just no way I am getting melasma from exposed skin!

Two brown patches are coming back and I can see them under foundation, which is such a disappointment after enduring 24 weeks of nonstop peeling and redness.

I don't understand how member ZOSKIN can say that Dr. Obagi no longer recommends long term hydroquinone use. Even on the ZO Skin website blog, Dr. Obagi often recommends to use Nuderm and then his products on non-Nuderm days. He always says you can never go off Nuderm (which I take means using hydroquinone) if you have melasma.

I had already used .1% tretinoin and Skinoren for a year before Nuderm and that combo removed 50% of the melasma. I am only trying to limit hydroquinone use because it plateaus and becomes ineffective long term. But now I have no idea what to do to keep the melasma from coming back fully. I don't want to be on the full NuDerm regime because that will also lose efficacy over time.



Is it terrible that I was secretly hoping you were going to say that you are using inadequate chemical sunscreen?? Because I have tried to convince myself that the majority of those who have had poor results with maintaining their nu derm results were due poor sun protection... Which is clearly not the case for you!! I'm actually kind of amazed at how similar our sunscreen protocols are... EVERY SINGLE DAY I apply Vivier c&e serum underneath Clarins UV HP + titanium based sunscreen, allow to set and then apply a generous layer of Fallene TiZo3 35 zinc oxide 20%. I then use Colorscience mineral SPF makeup and reapply Jane Iredale Powder-Me SPF several times throughout the day. My melasma and my desperate quest to rid myself of it has turned me into a sun protection maniac! I'm fortunate that my skin is so naturally pale that I can get away with the layers of physical sunscreen which often leave a white cast. I also never spend any time in the sun without a UPF rated wide brimmed hat as well as big sunglasses... Sad to admit that I am THRILLED that we have entered the fall/winter season in Vancouver, which means there's at least 6 months of short gray days with minimal UV (melasma has been such a lifestyle adjustment!)

I am also very surprised that Dr.Obagi no longer endorses regular (maintenance) use of his Nu Derm products. I haven't found any information to support this. I am hoping ZOSKIN can give us a little more info.

I have poured over every single piece of information I can online regarding melasma & hydroquinone. Many women have success clearing or dramatically fading their melasma with obagi, and are able to maintain the results. Some have even shared that they were able to discontinue hydroquinone and their melasma never returned. There are others, of course, which claim it didn't work for them, and unfortunately, even some that claim it made their melasma worse, which I HAVE to believe is a result of poor sun protection.

Did you experience total clearing of your melasma while you were on the full program? How frustrating to have it return so quickly. Did you use it under the supervision of a derm? I really feel for you!!

I am thinking of incorporating some of the NIA24 line into my off days on maintenance. Apparently they are quite effective for pigmentation issues....

Robyn
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Mon Oct 29, 2012 9:08 pm      Reply with quote
blanchedubois wrote:
I am also very surprised that Dr.Obagi no longer endorses regular (maintenance) use of his Nu Derm products. I haven't found any information to support this. I am hoping ZOSKIN can give us a little more info.

I have poured over every single piece of information I can online regarding melasma & hydroquinone. Many women have success clearing or dramatically fading their melasma with obagi, and are able to maintain the results. Some have even shared that they were able to discontinue hydroquinone and their melasma never returned. There are others, of course, which claim it didn't work for them, and unfortunately, even some that claim it made their melasma worse, which I HAVE to believe is a result of poor sun protection.

Did you experience total clearing of your melasma while you were on the full program? How frustrating to have it return so quickly. Did you use it under the supervision of a derm? I really feel for you!!

I am thinking of incorporating some of the NIA24 line into my off days on maintenance. Apparently they are quite effective for pigmentation issues....

Robyn


Hi Robyn,

I see that ZO Skin seems to be moving away from long term hydroquinone use but have never read any comments by Dr. Obagi where he prescribes a new regime for melasma patients. I have read nearly everything online about melasma from message boards to published studies and have not found any other alternatives than hydroquinone, tretinoin, azelaic and kojic acids, and arbutin. I do not believe hydroquinone makes melasma worse - it is not in your system after two weeks of stopping usage.

Read that hydroquinone does not work on some types of dermal melasma so maybe that is why Obagi didn't work for others. For me, I went from total strangers telling me I had dirt on my cheeks to nearly flawless skin in 24 weeks. For one whole week once I went on maintenance I didn't need any foundation or concealer - oh what a wonderful week with no more redness or peeling, just gorgeous skin. But now that the pigmentation is coming back, I am again flaking from using so many acids and tretinoin and can't even cover up the brown, sigh...

No, I didn't use it under continuous supervision of a derm but I did consult with Obagi office in HK and my friends used it at the same time under derm supervision. We had the same results. I used the most aggressive regime for maximum rejuvenation.

Are you seeing a derm? What does he/she recommend for your maintenance protocol?
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Tue Oct 30, 2012 11:25 am      Reply with quote
denisiel wrote:


Are you seeing a derm? What does he/she recommend for your maintenance protocol?


Well, I went to a clinic here in Vancouver, and instead of meeting with the actual dermatologist, I only met with his 'Clinician.' Apparently, in the case of this clinic, you only meet with the derm if you are considering lasers/injectables. I immediately found this offputting, but unforunately, found it to be the case with several of the clinics in Vancouver. Maybe this is typical everywhere, I don't know.

In any case, the 'Clinician' appeared to know less about both melasma and Obagi Nu Derm than I did (although, I really have become a bit of an expert due to a years worth of reading every piece of information I could find on the subjects.) Anyways, she looked at my skin, explained that it was a mild case of melasma, and that 18 weeks on Obagi would be all I need, and I could move to hydroquinone free products- no HQ maintenance necessary. Which I didn't believe, of course, but purchased the kit and went on my merry way. All in all the appointment was less than 10 minutes. She didn't offer any kind of follow up plan, and I quickly realized that I wouldn't be returning to that clinic.

In the meantime, I have found a female dermatologist with a private practice who seems to be very knowlegable when it comes to pigmentation issues, and I have made an appointment with her for the midle of next month, which is when I will begin maintenance. I am hoping that she can provide me with a maintenance program that will work.

By the way, when I said that I hope 'ZOSKIN' will offer more information, I was referring to the new forum member ZOSKIN, who had explained that Dr. Obagi no longer endorses continuous use of HQ.

I am really hoping that you are able to maintain your wonderful results by adjusting your maintenance routine. I know what you mean about shortening the daily application times... I find it a bit cumbersome too, because not only do I take the time to properly apply the Obagi products, but in the morning I have my borderline OCD process of applying layers of sunscreen. I would like to cut that back for sure.

It also sounds like neither one of us ever had that blissful 'skin adjusted' experience while on the full time program... The redness and peeling is still very much happening, though slightly less agressive than the first 6 weeks. I fully anticipate it will continue until I go on maintenance in a few weeks. I will say that I would happily take the redness and peeling over brown splotches scattered over my cheeks ANY DAY.

Have you considered incorporating the HQ free Clear & Blender with Arbutin now that you're on maintenance? I can find very little feedback on it online, and actually, the clinic I initially went to carried the HQ free Nu Derm kit, but when I asked what the feedback had been on it, she explained that in the 4 years of carrying it, they had never sold so much as one. I also wonder if moving to Arbutin is redundant as it appears to be very closely related to hydroquinone and behaves similarly on the skin...

I guess I'm just finding that it's really hard to be enthusiastic about my results when I have serious concerns on what it is going to take to maintain them. Rolling Eyes
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Thu Nov 15, 2012 12:01 pm      Reply with quote
ZOSKIN wrote:
I work at ZO SKIN HEALTH Inc. In 2012 we introduced Dr. Zein Obagi's newest creation of comprehensive skin health solutions, ZO Medical products; sold exclusively in physicians offices.

I work very closely with Dr. Obagi on new product development and I can confirm that he no longer recommends continuous use of HQ. (No more that 3-5 months) He has seen patients in his practice with severe skin pigmentation problems due to prolonged use of HQ. He developed a new non-hydroquinone product called BRIGHTENEX to address pigmentation issues. It is safe and ideal for maintenance after HQ therapy. Note: Dr Obagi is no longer affiliated with Obagi Medical Products.
Maybe that is why I have brown spots after using over 4 years of obagi..
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Thu Nov 15, 2012 12:02 pm      Reply with quote
What should I use for maintenance? If I don't use obagi, I will have my freckles back. Sad
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Thu Nov 15, 2012 2:58 pm      Reply with quote
Zoskin, please advise me.....
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Thu Nov 15, 2012 4:07 pm      Reply with quote
I've been using Obagi Nu-derm longer than you, but I don't have problems on maintenance at all and my skin is clear. Actually I am happy with the results, even with hydroquinone. Some people have problem using it, but I don't have issues using it. Of course, in order to protect my skin, I always use sunscreen ALL THE TIME......

Regarding ZOSKIN, I've been waiting to hear from him/her but no answer too! Brightenex (a new product as well) that ZOSKIN is recommending are only available at doctor's office!!!! I already spent so much on Obagi products over the years!!! And now I looked at Obagi website and it seeme Brightenex cost over $100 for a very small bottle!!! Even EDS do not carry it Sad

azumma wrote:

Maybe that is why I have brown spots after using over 4 years of obagi..
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Mon Nov 26, 2012 2:42 pm      Reply with quote
Me too. I spent too much money already. but I don't like my results. so Jade how long did you use Nuderm? what is your maintenance regime? I don't know I was happy about the result until June this year. my skin got sensitive to the Nuderm these days and the areas of brown spots (around my eyes and mouth) are getting worse and so itchy. how can I explain this??after peeling around the dry area, I can see the scar due to skin peeled off.

jade-1234 wrote:
I've been using Obagi Nu-derm longer than you, but I don't have problems on maintenance at all and my skin is clear. Actually I am happy with the results, even with hydroquinone. Some people have problem using it, but I don't have issues using it. Of course, in order to protect my skin, I always use sunscreen ALL THE TIME......

Regarding ZOSKIN, I've been waiting to hear from him/her but no answer too! Brightenex (a new product as well) that ZOSKIN is recommending are only available at doctor's office!!!! I already spent so much on Obagi products over the years!!! And now I looked at Obagi website and it seeme Brightenex cost over $100 for a very small bottle!!! Even EDS do not carry it Sad

azumma wrote:

Maybe that is why I have brown spots after using over 4 years of obagi..
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Mon Nov 26, 2012 9:25 pm      Reply with quote
We all spend too much money on skin-care Smile
I think I've been using since 2002 till now?
My maintenance regime is 3x a week only. The rest of the other days that I don't use Obagi Nu-Derm, I use different products to complement my results with Obagi Nu-Derm. During my journey until now, I always use a sunscreen no matter what day it is, but try to avoid intense UV rays during the days.
Also, you have to take into account as well that you bought your Obagi products somewhere else (not EDS), so probably a different formulation or fake ones that you got? Please don't poke your skin while it is peeling! Let it peel by itself....
azumma wrote:
Me too. I spent too much money already. but I don't like my results. so Jade how long did you use Nuderm? what is your maintenance regime? I don't know I was happy about the result until June this year. my skin got sensitive to the Nuderm these days and the areas of brown spots (around my eyes and mouth) are getting worse and so itchy. how can I explain this??after peeling around the dry area, I can see the scar due to skin peeled off.
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Tue Nov 27, 2012 12:55 pm      Reply with quote
adding these related posts

kd-ro wrote:
Hi there. I am new to this forum and it seems like it offers a lot of helpful advice. I am looking for a little guidance. I have been on Obagi Nu-Derm for about 10 days and although my skin is red, peeling and feeling very dry, I can already see very impressive results. I am 35 and have terrible melasma and very oily skin with occasional break outs (I just have bad skin in general). My forehead is almost full of brown patches and my cheeks are spotted with a few patches mixed in. I had terrible sun damage in my teens (I used to lifeguard), plus I think there is also a genetic factor involved as my mom has hyper pigmentation too. In addition to that, there is the hormonal component, birth control pills and then pregnancy. I had mild success with Tri-Luma a few years ago, but the melasma got really bad while I was pregnant. In just the 10 days that I have been using Nu-Derm, my spots have faded about 40% and my pores are almost invisible. My brow lines have almost diminished as well and my skin is very smooth.

Finally getting around to my question...I understand that in order to keep the results after I complete the Nu-Derm system, that I need to continue using the products a few times a week in a maintenance program. My concern has to do with the use of hydroquinone. I know there is a lot of controversy out there about it being a carcinogen. I would prefer to use something a little safer when it comes time for the maintenance protocol. Has anyone used the Clear FX and Blender FX in place of the Clear and Blender with any success? What about another alternative to keep the pigmentation at bay? I would also like to use something that would be safe during pregnancy as we may decide to have another child in a couple of years. Any advice you could offer would be greatly appreciated. Thank you!


azumma wrote:
Where can I buy obagi nuderm fx clear and blender? Not in here EDS..


jade-1234 wrote:
Hi azumma Smile You can buy at EDS, see link below...
http://www.essentialdayspa.com/obagi-clear-blender-sunfader.htm

azumma wrote:
Where can I buy obagi nuderm fx clear and blender? Not in here EDS..
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Tue Nov 27, 2012 1:03 pm      Reply with quote
denisiel wrote:
Now I am worried that if Dr. Obagi doesn't recommend hydroquinone use after Nuderm then what can keep the pigmentation from returning? Kojic acid, azelaic acid and arbutin don't wipe out the brown areas, they just lessen the effect.


This is from one of the ZO press releases:

Quote:
ZO® MEDICAL is Dr. Zein Obagi’s new generation of therapeutic skin care based on his new thinking and reflecting his views on the need to regulate and limit the usage of hydroquinone and retinoic acid for three to five months of treatment. Once therapeutic treatment is complete alternative topical agents should be used. Together with the ZO® SKIN HEALTH line he introduced in 2008, they complete Dr. Zein Obagi’s ZO® Skin Health Circle™. The products have been created to address a wide range of skin disorders and chronic conditions. With decades of science and experience invested in its development, ZO® MEDICAL by Zein Obagi, MD is suited for everyone, regardless of skin condition, age, gender, or ethnicity.

Dr. Zein Obagi says, “My new line of therapeutic skin care is raising the bar of skin health: a concept I created over 25 years ago and which represents my new thinking of skin health completing my ZO® Skin Health Circle™. It is now a reality”.

http://www.zoskinhealth.com/dr-zein-obagi-founder-zo-skin-health-inc-announces-launch-zo-medical-raise-bar-skin-health


Quote:
Dr. Zein Obagi says "Move over Hydroqinone! ZO Skin Health, Inc. has found a new way to inhibit melanogenisis and reverse hyper pigmentation."

Brightenex™ is positioned to lead the category of topical hyperpigmentation solutions. It is the first commercial product launch that stabilizes pure retinol (1.0%), melanin inhibitors and antioxidants with natural, patented Oleosome technology. Oleosomes are microspheres of antioxidant-rich emollient oils and vitamins found naturally in plant seeds like almond and safflower. As these microspheres release, they provide immediate moisturization benefits to skin. By stabilizing and delivering retinol, Oleosome technology also provides a delayed release of active ingredients, reducing potential irritation while improving performance.

http://www.zoskinhealth.com/professionals/press/103
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Tue Nov 27, 2012 1:12 pm      Reply with quote
jade-1234 wrote:
Also, what is the main ingredients of Brightenex that will even out or lighten skin tones?


Here's the overview on Brightenex from the ZO website:

BRIGHTENEX™ Multi-Action System
• Dual pigmentation reversal with vitamin A and ascorbic acid-2 glucoside
• Bio-active levels of vitamins E and C, and stachys officinalis antioxidants
• Multistage glutathione, soy isoflavones, and N-acetyl glucosamine melanin inhibitor system
• Retinol (1.0%) microencapsulation in an oleosomes delivery system

Ingredients: Water (Aqua), Cetearyl Isononanoate, Cyclopentasiloxane, Prunus Amygdalus Dulcis (Sweet Almond) Oleosomes, Cyclohexasiloxane, Glycerin, Cetearyl Alcohol, Steareth-20, Pentylene Glycol, Cetyl Alcohol, Polysorbate 20, Retinol, Ascorbyl Glucoside, Propylheptyl Caprylate, Ascorbyl Palmitate, Glutathione, Stachys Officinalis (Leaf) Extract, Acetyl Glucosamine, Prunus Armeniaca (Apricot) Kernel Oil, Tocopheryl Acetate, Nylon 12, Sodium Sulfite, Zea Mays (Corn) Oil, Beta-Carotene, Sodium Metabisulfite, Soy Isoflavones, Lecithin, Acrylamide/Ammonium Acrylate Copolymer, Polyisobutene, Cetearyl Glucoside, Alcohol, Polysorbate 80, Carbomer, Sodium Hydroxide, Disodium EDTA, Potassium Sorbate, 1,2 Hexanediol, Caprylyl Glycol, Pelargonium Graveolens Flower Oil, Lavandula Angustifolia (Lavender) Oil
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Wed Nov 28, 2012 12:53 pm      Reply with quote
For those people who are interested in Brightenex and living in Canada--- Brightenex is not available as yet pending approval from Health Canada.... Reply received Nov28/12 this morning from ZO authorized distributor in Canada.
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Wed Nov 28, 2012 5:11 pm      Reply with quote
Thank you very much for the post, jade. Razz
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Wed Nov 28, 2012 6:07 pm      Reply with quote
You are welcome. I will update this forum once I hear any further news..
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