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Local Medspa Offering Dysport as alternative to Botox?
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Barefootgirl
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Tue Jun 30, 2009 7:04 pm      Reply with quote
What is Dysport? Comments? Experiences?
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Tue Jun 30, 2009 8:14 pm      Reply with quote
Barefootgirl wrote:
What is Dysport? Comments? Experiences?


It is a newly released Botox alterative that works faster and lasts longer. I would try it in a heartbeat.

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Tue Jun 30, 2009 11:47 pm      Reply with quote
Barefootgirl wrote:
What is Dysport? Comments? Experiences?


Dysport is also a Botulinum Toxin type A, like botox. The difference is that they come from a different strain of the bacteria.

While anecdotal evidence cited mostly by Dysport says that "many cosmetic physicians who have used Dysport report faster action and greater longevity for Dysport when compared to Botox", there is not research studies to back this claim up. In fact, there is not a lot of research done comparing Dysport with Botox, but the trials done on patients have shown that botox has a higher patient satisfaction, lasted longer, and had less complications. Dysport has a lower molecular weight than Botox so it "difuses" more rapidly. While this diffusing might be the cause of the reported "faster action", it is also the cause of more complications, since the toxin can diffuse to unwanted muscles.

On a review of trials of Botox and Dysport (in any place of the body), there was no statistically significant difference in the magnitude of effect or duration between Botox and Dysport, except when used for cervical dystonia, where Dysport lasted longer but also was associated with adverse effects (Movement Disorders 2004; 19(Suppl.8 ): S129–S136). However a more recent systematic review ( Clin Ther. 2007 Jul;29(7):1325-37) found that Botox lasted longer and had less adverse effects when used for cervical dystonia.

In the latest review (Plast Reconstr Surg. 2008 Jun;121(6):413e-422e) comparing clinical trials for wrinkles, Botox had a better safety margin, and either lasted longer or the same as Dysport.

I think one of the main problems with Dysport is that the optimum dose has not been really found yet, with results varying quite a bit, while it's a lot more established with Botox.

Having said all this, Dysport has proven to be safe. If the price difference is not too much, I would stick with Botox. And if someone's offering Dysport, I would check that they went to special training for Dysport (as opposed to just switching) because it's tricky.

I hope this helped!

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Determined
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Wed Jul 01, 2009 1:37 am      Reply with quote
Josee, thank you so much for your informative answer. It was exactly the info I was looking for -
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Wed Jul 01, 2009 5:26 am      Reply with quote
Both my daughter and I had Dysport at the same time (we thought we were getting Botox). We were both unsatisfied with the results so we went back to the clinic. That was when we were informed that we had not been given Botox but Dysport - the nurse told us that she would re-inject with Botox and that different people have different reactions to both muscle relaxers.

To my knowledge, Dysport has been around for quite some time and is commonly used in Asia (I believe it is quite often given in place of Botox so it pays to ask what you are actually paying for). I have never heard of any negative experiences concerning Dysport (despite my own, which could have been the fault of the injecting nurse).

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Wed Jul 01, 2009 7:27 am      Reply with quote
Determined wrote:
Josee, thank you so much for your informative answer. It was exactly the info I was looking for -


I just re-read my post and just wanted to clarify that Dysport has been used safely for years as well and the rate of complications is very small. I think my post sounded too "anti-Dysport".

I think the bottom line is:

- More research needs to be done comparing Botox with Dysport for facial dynamic wrinkles. The little research available shows slight superiority of Botox.

- The biggest challenge for Dysport now is to find the correct dosage that will give the optimal relationship between efficacy and safety

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Barefootgirl
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Wed Jul 01, 2009 11:01 am      Reply with quote
Thank you all very much for your comments and input.

I just noticed the price difference between Dysport and Botox is significant. This medspa is offering Dysport at $4/unit and Botox at $10/unit.

Of course, I would like to try the Dysport, but wonder how much I would need as compared to Botox treatments in the past. For example, I have been getting 8 units of Botox on each side for crows feet, so 16 units altogether.

I have read the Dysport is more concentrated - but if the medspa dilutes it further - this might not even make a difference (?)

Also, if Dysport does not offer the same results for me, I guess I should ask them to re-do with Botox - but hate to pay twice Sad

BF
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Wed Jul 01, 2009 11:19 am      Reply with quote
Barefootgirl wrote:
Thank you all very much for your comments and input.

I just noticed the price difference between Dysport and Botox is significant. This medspa is offering Dysport at $4/unit and Botox at $10/unit.

I have read the Dysport is more concentrated - but if the medspa dilutes it further - this might not even make a difference (?)

Also, if Dysport does not offer the same results for me, I guess I should ask them to re-do with Botox - but hate to pay twice Sad

BF


Hello Barefootgirl,
It's actually the other way around... Botox is more potent than Dysport.
So in general... the ratio used is between 2:1 to 4:1. This means that, to achieve the same effect, for every unit of Botox, you would have to inject 2-4 units of Dysport.

What you might have read as "concentrated" could mean that the amount of units per ml. can be higher in Dysport. This is because if you used Dysport at the same concentration than Botox, you would have to end up injecting more ml in your muscles. The more mls, the more change of the toxin diffusing to unwanted muscles.

Ask in your medispa which conversion ratio the use Botox:Dysport to get an idea.

For e.g. in a trial of Dysport vs. Botox for glabellar lines (Dermatol. Surg. 31: 1651, 2005), the authors concluded that in a 2.5:1 ratio, Botox had more prolonged efficacy.

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Thu Jul 02, 2009 8:32 pm      Reply with quote
We've had dysport in Australia for years. I started to develop a resistance to botox, and my Dr tried dysport to see if it would work any better for me. It didn't.
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Fri Jul 03, 2009 12:40 pm      Reply with quote
Mishey wrote:
We've had dysport in Australia for years. I started to develop a resistance to botox, and my Dr tried dysport to see if it would work any better for me. It didn't.


Drat..I am somewhat Botox resistant, so I was hoping that Dysport might be an option for me. Sad

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Fri Jul 03, 2009 1:22 pm      Reply with quote
Mishey wrote:
We've had dysport in Australia for years. I started to develop a resistance to botox, and my Dr tried dysport to see if it would work any better for me. It didn't.


Both Dysport and Botox are Botulinum Toxin type A, so if you have resitance to Botox you will have resitance to Dysport. In fact there is absolutely nothing in the literature, not even case reports, of Dysport working for patients who had resitance to Botox.

What some doctors are using, with varying degrees of satisfaction, is Myobloc, which is type B botulinum toxin.

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Keliu
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Sun Jul 12, 2009 3:39 am      Reply with quote
In an article about Botox in his month's Australian Vogue magazine it says that Korea's Medy-Tox has developed its version of Botox called Neuronox, and claims it delivers the same results at a lower price. It goes on, "German pharmaceutical giant Merz says Xeomin, its version of botulinum toxin, is more innovative and claims its formulation has purified away the "complexing proteins" that cause immune reactions such as antibody formation, thus providing a longer effect. Both manufacturers are applying for use here (Australia)."

"Another botulinum toxin brand, Reloxin, is currently being released in the US; we've had something identical here for years - the French version, Dysport".

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Thu Mar 14, 2013 8:35 pm      Reply with quote
I had my second or maybe it was third treatment with Dysport. Lasts about five months on me. I had used Botox previously about three times and the last time it didn't seem to last as long so my derm said I might be immune to it. Fingers crossed with the Dysport. While I was in the office, the nurse handed me a brochure about Xeomin which is a bit cheaper. My derm explained that the proteins surrounding the botulism are different in Botox and Dysport but that the Xeomin doesn't have any. I don't know if I want to try something that my body couldn't fight against if it had to. She also felt that the jury was out on the safety and effectiveness but I notice this thread is four year old now. Sounds like other countries have been using it longer than the US.

If it's just as safe as Botox and Dysport and lasts as long but is cheaper, I'd definitely get it. Today I had my frown line (only have one) and crows feet done for $195.

My next big expense is getting more Restylane in my tear troughs as the last batch is going away now. Very expensive through my oculoplastic surgeon. I have a lot of scar tissue underneath the skin due to removal of fat bags years ago so he really struggles pumping filler in there and I always end up bruised.

How we suffer for beauty!
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Fri Mar 15, 2013 5:36 am      Reply with quote
I have found it sets up much faster than Botox, I just had it done last month so I can't speak to it lasting longer.

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Fri Mar 15, 2013 10:14 pm      Reply with quote
LauraLizzie wrote:
I have found it sets up much faster than Botox, I just had it done last month so I can't speak to it lasting longer.


Which one are you talking about?

I had Dysport yesterday but I can still frown. Crows feet are slightly better. Hope there is more improvement.
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Fri Mar 15, 2013 11:30 pm      Reply with quote
BFG I use Dysport and its absolutely fine on me. I find it doesnt totally freeze my skin like botox, if that makes sense, and I actually prefer it over botox.
It lasts 4 months on me. I have no issues whatsoever...so far..so good. My Dr, whom I trust, assured me that its been around and used for a very very long time, as you know. Just wanted to share my experience with both
Goodluck Smile
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Sat Mar 16, 2013 10:12 am      Reply with quote
In my experience botox is far more effective than Dysport. The only time I have experienced 'eye droop' was after being injected with Dysport - in fact, as noted above, this could have been caused by the 'spreading' of the Dysport. Botox, when correctly diluted, seems to last considerably longer - 4-5 months as opposed to 3 months or less with Dysport. Dysport may be suited to younger women? I too have found that I am often presented with Dysport by the practitioner, even when my appointment is for Botox. Take note of this. I am in Florida and have found most medical spas are charging the same for both. I am concerned about over dilution, and shelf life of the product. I always ask for a fresh vial of botox, again - it seems its efficacy is reduced if it has been sitting around in the fridge too long. Lastly, I have to question the trend to charge per area, ie. Forehead, crows feet, frown lines. Whats up with that? An older women would surely require more botox than one younger, they should charge per unit.
Good luck.
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Sat Mar 16, 2013 4:03 pm      Reply with quote
A friend of mine got some dysport for her forehead wrinkles. They were very severe. The dysport made them pretty much disappear. She was thrilled! Now she gets it every 3 months I think.

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Sat Mar 16, 2013 6:07 pm      Reply with quote
SoftSkin wrote:
LauraLizzie wrote:
I have found it sets up much faster than Botox, I just had it done last month so I can't speak to it lasting longer.


Which one are you talking about?

I had Dysport yesterday but I can still frown. Crows feet are slightly better. Hope there is more improvement.


Sorry, I was talking about Dysport. It takes me 10 days or maybe 7 days for Botox to completely kick in. Dysport was 1-3 days to full set in.

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