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Retinol vs tretinoin, when to switch?
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kitkat11
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Sun Jun 05, 2016 6:26 pm      Reply with quote
I've been using 1% retinol (Paula's Choice Clinical 1%) for about 6 months now, primarily for anti aging/rosacea with success. I've built up slowly to using it nightly and I've definitely noticed results.

My derm has suggested I start a prescription of tretinoin at 0.018%. But I don't really understand why. I've read from multiple sources that retinol is comparable to 0.02% tret. So in theory the new prescription would be the same thing. She agreed with what I said but seemed to imply the tret was still better without giving me a solid reason why. She's not interested in going past 0.018% either.

Since I'm new I can't make links, but a study called "A Randomized, Double-blind, Split-face Study Comparing the Efficacy and Tolerability of Three Retinol-based Products vs. Three Tretinoin-based Products in Subjects With Moderate to Severe Facial Photodamage" seems to conclude they're comparable.

If this is all correct, switching to Peter Thomas Roth's 1.5% retinol formula would actually be a nice boost over the proposed tret prescription.

What do you think?
TheresaMary
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Mon Jun 06, 2016 2:01 am      Reply with quote
Retinol is very different to Tretinoin although they do produce similar results (just tretinoin works faster) so your derm suggesting moving to tretinoin is probably because it is going to get you faster results. They are very different and work differently for different people. Tretinoin has more studies on it than any other topical out there so its definitely got benefits to it. Plus its been around for countless years (I’ve used it 30 plus).
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