Great new DNA (Renovage/Trepenone) product from Nanci !!!!!!
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free skin care · Sat Nov 26, 2011 4:42 am

I'm re-posting my post from a few weeks ago:

Keliu wrote:

In general, I'm confused about the results that people do see. I understand the difference of skin being too dry and how much better it can look when thoroughly hydrated from within and without. But I don't understand how skin can physically regenerate in a matter of days. We're told that results from the use of Retin-A can take up to a year to show. Even invasive treatments like IPLs, lasers or RF take between six months to a year to improve the skin.

Yes, there are certain actives that will stimulate the growth of collagen and elastin - but this also takes months. And on top of that you have to factor in age - as mature aged skin is losing collagen at a faster rate than young skin.

I definitely believe in using proven ingredients and using appropriate skincare gadgets. And from doing so, I think my skin looks allot better than many women my age. But I'm afraid I'm just not one of those people who squirts something on my face at night and wakes up the next morning to see a brand new me staring back!

And here is what Nanci has to say on the subject taken from the link provided by Riley:

Quote:

Generally speaking, you can START to see results with the products in a couple of months. But I think that six months is the magic number for most of the “active” products. For some, depending on your individual skin and its condition, it could take up to a year.

You may notice immediate results with some of them – like the CP Accelerator, EGF Serum or the DNA Serum for example. However, those are most likely moisture retention or skin softness. For some (you’ve probably read about them in my blog), results including lifted skin and lines/wrinkles diminished is a reality after a short period of time. But for the most part, these products do not work so fast – and that’s expected. Your skin didn’t get the way it is overnight so it’s not going to look 10 years younger overnight. DNA Serum extends cell life – you will age slower.

Thank heavens for a Voice of Reason - and the seller too!

free skin care · Sat Nov 26, 2011 6:35 am

Does anyone have concern over this type of information?

Teprenone is the brand name for a drug known as geranylgeranylacetone, which is used to treat gastric ulcers and is being researched as an option for slowing age-related hearing loss (Sources: Brain Research, May 2008, pages 9–17; and Digestion, October 2007, pages 215–224). What do hearing loss and ulcers have to do with aging skin? One of the key ways geranylgeranylacetone works is by influencing heat-shock proteins, which help other proteins interact as they should at the cellular level, which in turn affects many systems in the body. Heat-shock proteins are most active during times of stress, such as exposure to cigarette smoke and exposure to sunlight.

When heat-shock proteins are reduced (which ultimately is what you want because that means reducing skin inflammation—think inflamm-aging), cells appear to live longer. Some cosmetic companies have theorized that geranylgeranylacetone (as Teprenone) also may have a helpful effect when applied topically. Perhaps their logic went something like this: The skin is the body’s largest organ, it produces a lot of heat-shock proteins because it is exposed to environmental and physical stresses, so ingredients that help reduce these damaging proteins will be of benefit.

The problem? There’s no research that topically applied geranylgeranylacetone has any effect on heat-shock proteins in skin. Moreover, any cosmetic company whose products contain teprenone means they're using a drug ingredient in a cosmetic product, so the consumer is the guinea pig.

free skin care · Sat Nov 26, 2011 6:46 am

AmazingRacer - where did you find the above information? Can you provide us with the link.

free skin care · Sat Nov 26, 2011 7:35 am

Keliu wrote:

AmazingRacer - where did you find the above information? Can you provide us with the link.

Not sure where AmazingRacer found the info, but here is a link with the same info.

http://www.cosmeticscop.com/cosmetic-ingredient-dictionary/definition/1681/teprenone.aspx

Here is what middle-ageless and truth in aging have posted about teprenone/renovage:

http://middle-ageless.com/?p=1313

http://truthinaging.com/ingredient-spotlight/telomeres-and-renovage-may-provide-the-secret-of-aging

free skin care · Sat Nov 26, 2011 10:45 am

Thanks for those other links about the ingredient. Yes, my info came from the same one posted (cosmeticscop). Obviously the NCN DNA serum fans here probably aren't concerned about the negative or neutral things said about the ingredients. I just wondered if anyone is. I'm liking my sample and need to decide quick whether or not to buy it at 20% off.

free skin care · Sat Nov 26, 2011 12:50 pm

AmazingRacer wrote:

Obviously the NCN DNA serum fans here probably aren't concerned about the negative or neutral things said about the ingredients. I just wondered if anyone is. I'm liking my sample and need to decide quick whether or not to buy it at 20% off.

I think the problem is that skin care, in general, has not been around long enough to know if any of the ingredients (other than the "proven" ones) are harmful or not. I struggle with this issue a lot, to be honest with you, because we just don't know the long-term outcome of most of the ingredients out today.

I did purchase the full size bottle, and I wanted to let you know that the consistency/texture of the product in the bottle is different than that of the sample (or at least different from my sample!). The sample I had was almost an oil consistency, while the serum in the bottle appears to be more of a true "serum" consistency.

free skin care · Sat Nov 26, 2011 1:00 pm

rileygirl wrote:

I did purchase the full size bottle, and I wanted to let you know that the consistency/texture of the product in the bottle is different than that of the sample (or at least different from my sample!). The sample I had was almost an oil consistency, while the serum in the bottle appears to be more of a true "serum" consistency.

Thanks. My sample almost looks like it separates, so I think I know what you mean about oily. But it's very watery, or maybe it's just difficult when you're dispensing it out of that little packet. I'm probably going to order a full size bottle, along with the 20% Matrixl (any great reviews on that one?).

free skin care · Sat Nov 26, 2011 8:08 pm

AmazingRacer wrote:

......I'm probably going to order a full size bottle, along with the 20% Matrixl (any great reviews on that one?).

I have used the 20% Matrixl for 6 months (day & night) and found that I should have spent money elsewhere.

free skin care · Sun Nov 27, 2011 4:15 am

Taken from NCN website:

"NANCI RECOMMENDS

In the morning, I’m using DNA Serum after Collagen-Elestan Lifting Serum and before my CP Accelerator. At night, I’m using it after my Collagen-Elestan Lifting Serum and before my All-Trans Retinol 2.0%.

If you use Retin-A, or any form of tretinoin, Retin-A goes on your skin first. Wait 20-30 minutes and apply DNA Serum. If you are layering products, please refer to the Product Instructions that are on the top menu bar of every page. They show the order in which to apply the products."

...apparently retin-a goes on first, then the DNA. I just wonder if there is any benefit of using both together or if this is just a "in case you don't use retin-a alone" type of thing. I have always used retin-a straight up, nothing else. But, if there's some form of benefit of using both together I would certainly try it.

free skin care · Sun Nov 27, 2011 4:18 am

summer2004 wrote:

AmazingRacer wrote:

......I'm probably going to order a full size bottle, along with the 20% Matrixl (any great reviews on that one?).

I have used the 20% Matrixl for 6 months (day & night) and found that I should have spent money elsewhere.

I've used NCN's 20% Matrixyl serum in the past and absolutely loved it before switching to my sis's DIY. But I think the formula changed since I used it last.

free skin care · Sun Nov 27, 2011 4:20 am

Why does the retin a go on first, but the trans-retinol go on last?

free skin care · Sun Nov 27, 2011 4:29 am

Lotusesther wrote:

Why does the retin a go on first, but the trans-retinol go on last?

Maybe because it is an actual medication and medications should be applied to clean skin.

I always apply Retin-A last because I often apply my other serums and use skincare gadgets. Using skincare gadgets over Retin-A is a no-no I believe.

Personally, I do not believe the efficacy of Retin-A is compromised by applying it on top of other products.

free skin care · Sun Nov 27, 2011 7:11 am

bren21 wrote:

I just wonder if there is any benefit of using both together or if this is just a "in case you don't use retin-a alone" type of thing. I have always used retin-a straight up, nothing else. But, if there's some form of benefit of using both together I would certainly try it.

I personally don't think there is any benefit to using both at the same time, but more what you said "in case you don't use RA alone" type deal! I am only using the DNA Serum once a day in the morning. Does anyone know how long it will last using just once a day?

AmazingRacer (do you watch that show, BTW? I love it!), I have never gotten any benefit from Matrixyl. Unfortunately, I think all of this is YMMV!

free skin care · Sun Nov 27, 2011 4:37 pm

bren21 wrote:

...apparently retin-a goes on first, then the DNA. I just wonder if there is any benefit of using both together or if this is just a "in case you don't use retin-a alone" type of thing. I have always used retin-a straight up, nothing else. But, if there's some form of benefit of using both together I would certainly try it.

There are those who believe that if they are using Retin-A they are doing the best for their skin that they can, so other products should not be necessary. That may very well be true. But I prefer not to put all my eggs in one basket and I also can't stand the thought that I might be missing out on something. So I basically try everything - I'm also desperate!

free skin care · Tue Nov 29, 2011 5:30 am

Keliu wrote:

bren21 wrote:

...apparently retin-a goes on first, then the DNA. I just wonder if there is any benefit of using both together or if this is just a "in case you don't use retin-a alone" type of thing. I have always used retin-a straight up, nothing else. But, if there's some form of benefit of using both together I would certainly try it.

There are those who believe that if they are using Retin-A they are doing the best for their skin that they can, so other products should not be necessary. That may very well be true. But I prefer not to put all my eggs in one basket and I also can't stand the thought that I might be missing out on something. So I basically try everything - I'm also desperate!

I hear ya on that. Nothing wrong with being a trail blazer and trying what you can! Smile

My DNA arrived yesterday...I used it last night. Applied it about 30 minutes before bed and then put a thin layer of Emu just before hopping in. I just started a week or so ago applying Emu twice daily (Only on nights I don't use retin-a and I mix 2 drops with my MSM cream in AM). Lets hope I get some added moisture like many have gotten a few weeks out with the old DNA!

free skin care · Tue Nov 29, 2011 7:39 am

Has anyone had any breakouts with the DNA Serum? I find I am getting a few pimples (!) and am just curious if anyone else has had this?

free skin care · Tue Nov 29, 2011 4:20 pm

I've had some riley and it took a while for them to clear up for me. (Sigh)

At least they weren't very big ones and the marks from them healing were small as well.

Right now I'm trying the one for oily skin under my eyes, neck and hands. I did also use it on my nose when I had a cold and it worked GREAT on the red, rough skin from all the blowing I had to do. And - no breakouts in that area during that time (about 2 weeks)

free skin care · Wed Nov 30, 2011 3:42 am

rileygirl - No, quite the opposite as I appear to have experienced less blemishes! I think mine tend to be the occasional hormonal type, if that makes any difference.

free skin care · Wed Nov 30, 2011 6:21 am

Thanks, Foxe and Majorb. Mine are small, and already starting to vanish so I will continue on! I am also using the EGF caps and not sure if it was from them or the DNA serum.

free skin care · Tue Dec 06, 2011 8:57 pm

From Nanci's site - didn't know if anyone saw this in Bold....
You may notice immediate results with some of them – like the CP Accelerator, EGF Serum or the DNA Serum for example. However, those are most likely moisture retention or skin softness. For some (you’ve probably read about them in my blog), results including lifted skin and lines/wrinkles diminished is a reality after a short period of time. But for the most part, these products do not work so fast – and that’s expected. Your skin didn’t get the way it is overnight so it’s not going to look 10 years younger overnight. DNA Serum extends cell life – you will age slower.

I have been very happy with this product - DNA Serum - have been using for a few months now. I've also started using trans-retinol 2% in place of retin a.

free skin care · Tue Dec 06, 2011 8:58 pm

From Nanci's site - didn't know if anyone saw this in Bold....
You may notice immediate results with some of them – like the CP Accelerator, EGF Serum or the DNA Serum for example. However, those are most likely moisture retention or skin softness. For some (you’ve probably read about them in my blog), results including lifted skin and lines/wrinkles diminished is a reality after a short period of time. But for the most part, these products do not work so fast – and that’s expected. Your skin didn’t get the way it is overnight so it’s not going to look 10 years younger overnight. DNA Serum extends cell life – you will age slower.

I have been very happy with this product - DNA Serum - have been using for a few months now. I've also started using trans-retinol 2% in place of retin a.

free skin care · Tue Dec 06, 2011 9:12 pm

I posted this a few posts back after Riley provided the link. What you haven't highlighted is "However, those are most likely moisture retention or skin softness".

free skin care · Tue Dec 06, 2011 9:31 pm

A nice product. Is all I'm saying.

free skin care · Wed Dec 07, 2011 5:23 am

sister sweets wrote:

A nice product. Is all I'm saying.

Although I have had no instant plumping or "cushioning" I'm going to continue with this product. It fills my essential five criteria, which are: doesn't break me out, doesn't irritate my Sebaceous Hyperplasia, doesn't ball up and is reasonably priced.

BTW, the unusual smell is very familiar to me. I can't remember where I've smelt it before - could it have been in a SkinActives product?

free skin care · Wed Dec 07, 2011 6:57 am

I've been using the DNA since the end of November which puts me at about 8 or 9 days. Although I haven't noticed any plumping or cushioning, I have noticeable improvement of hydration in my under eye area in the fact that my "late in the day" accordion look under my eyes and towards the outsides when I smile is pretty much gone. The outer is completely wiped out. Which is great because now I don't feel so self conscience when smiling Very Happy

I have also taken note of the fact that my tuck serum works much better since I started using this...it just looks more natural.

The one thing I hate about the serum: the pump bottle!! Terrible for dispensing even with trying to pump half way and slowly in my cupped hand. The pump is simply just not "fluid" enough and has too much resistance for such a thin consistency serum. I will have to rebottle this in something else as it is quite a pain.

But all in all, I am very happy with what I see thus far and if all it ever does is give me more hydration under my eye area then it's still money well spent! For the amount you get and the amount you use it's a great bargain. I could see this lasting me several months. I look forward to the coming weeks to see if I get any plumping...

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