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The better UVA blocker: tinosorb or Mexoryl?
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wanghaha
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Fri Oct 24, 2008 10:22 am      Reply with quote
I have freckles and get sunburned easily, so I am always wearing sunscreens during the day. I started to buy sunscreens with Mexoryl from New Zealand and Hong Kong via Internet 3 yrs ago despite all the hassles. The NZ website does not sell Mexoryl sunscreens anymore.
Thus I went out looking for other sources to buy good sunscreens. Recently, I heard another photostable UVA blocker; tinosorb. Is this a comparable or even better UVA blocker?

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wanghaha
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Fri Oct 24, 2008 6:08 pm      Reply with quote
I found some good discussion in the old posts. So my question could be considered answered.
Cool

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Stardustdy
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Fri Oct 24, 2008 7:32 pm      Reply with quote
so wanghaha, which's better then? Tinosorb or Mexoryl? Smile
wanghaha
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Sat Oct 25, 2008 8:44 am      Reply with quote
There is no simple answer because there is no head-to-head clinical comparison between the two. Although head-to-head trial is risky, it has been done a lot in pharmaceutical industry (where I work) to get market share. I guess SS market is large enough that no need to risk.

I found clinical data (skin biopsy) (by L'oreal) on Mexoryl. But no such data on the other. Since mexoryl SS works for me, I will stick to Mexoryl for now.

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Sat Oct 25, 2008 12:41 pm      Reply with quote
I guess Tinosorb is effective in the UVA protection too but since it's quite new, so perpahs no data has been established yet?
wanghaha
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Sat Oct 25, 2008 4:22 pm      Reply with quote
While clinical trial data is mandatory for new drugs, it is probably not required for SS in Euro. L'oreal did a controlled clinical trial quite early on Mexoryl SX and the measurement was from skin biopsy. Clinical trials are very expensive. I am not surprised that no controlled clinical data on Tinosorb.

In US, to get FDA's approval on a new UV blocker requires a NDA (new drug application) because it is treated the same as a medicinal new compound. It needs a lot of work to show efficacy and safety and costly to get the data. This certainly prevent companies getting approval for ss in US.
Until FDA changes its way to deal with UV blockers, I don't expect to see Tinosorb SS or high potent Mexoryl SS sold in US anytime soon. Sad

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