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DMAE
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passionfruit
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Sun Sep 24, 2006 4:37 pm      Reply with quote
I am knew to this site and have been reading about DMAE which i have never heard of. I read in one post that you can make this yourself and would appreciate anyones help in telling me how. I do love this site and have ordered products based on your reviews.

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Sun Sep 24, 2006 5:16 pm      Reply with quote
Hi,welcome to the Board. I love DMAE,if you do a search and look it up. Tons of info.And not sure,but might be some recipes on the DIY.One thing I found after a bunch of searching and trying produts,is that the "amine"form of DMAE works very well. I made some from the bitarate form and it doesnt do anything.Dr Perricone,I beleive brought this to the market.I have just ordered some from Garden of Wisdom,I will gladly share my opinion after I give it a try.
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Mon Sep 25, 2006 7:13 am      Reply with quote
Passionfruit, what a beautiful name,
welcome to EDS. My understanding about DMAE is that it's used to help skin that is starting to sag, like around the jawline. It come in different % and can be in a serum or cream and it has a bit of an odor. I order mine from Nature's Pharmacy in Ashville, N.C.-ask for Kerbie and ask for the odorless. I started with the 3% serum and now have started to use the 6% serum. Does it work? I think so-my 52 yo sagging jawline look alittle better than before I started w/ it. Not sure if it does much for young skin?
c4ward
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Mon Sep 25, 2006 11:41 am      Reply with quote
Hi. I use the Jan Marini Transformational serum which has DMEA. I'd love to find something cheaper. Any recommendations?

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PocoLoco
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Mon Sep 25, 2006 1:52 pm      Reply with quote
Check outwww.skincarecentral.biz. They have 2% and 4% DMAE (amine) in a clean formulation.
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Mon Sep 25, 2006 2:38 pm      Reply with quote
Pocoloco, you're my skin knowledge hero. I went on the web site and was wondering what heading the DMAE was sold under? Thanks in advance.

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PocoLoco
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Mon Sep 25, 2006 3:13 pm      Reply with quote
Embarassed Very Happy

Looks like Kathleen's been too busy to add these products to her main site. Here they are on her private skincare page:

http://www.skincarecentral.biz/skincare-private.html
c4ward
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Mon Sep 25, 2006 3:23 pm      Reply with quote
Thanks Pocoloco! Very Happy

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Tue Sep 26, 2006 1:51 am      Reply with quote
PocoLoco wrote:
Check outwww.skincarecentral.biz. They have 2% and 4% DMAE (amine) in a clean formulation.


i couldn't find a dmae product from the site.
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nomoreneckpain
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Tue Sep 26, 2006 3:59 am      Reply with quote
c4ward, I'm not sure what comparable product costs elsewhere since I;ve been ordering from this compound pharmacy. I paid 29.99 w/ 7.00 s/h usd for 30gms glass bottle w/ dropper 6% DMAE serum-odorless/clean formulation. You use very little. HTH.
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Tue Sep 26, 2006 8:28 am      Reply with quote
felinehhy,

The DMAE is on the same page that I provided the link for, directly above your post... Smile
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Tue Sep 26, 2006 6:58 pm      Reply with quote
PocoLoco wrote:
felinehhy,

The DMAE is on the same page that I provided the link for, directly above your post... Smile


thank you,i will try again Wink
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Tue Oct 03, 2006 7:44 am      Reply with quote
I received a sample of DMAE fromwww.skincarecentral.com. Now I'm wondering how to use it!

I hope DMAE mavens can give me some ideas about when and how to apply it (I use Vit.C serum and I'm guessing I should apply DMAE between that and my sunscreen).

Also, how long before any results are noticeable? A few years ago, I tried a Perricone DMAE product after reading his pamphlet, "The Wrinkle Cure". In it, he claimed almost immediate results (lifting) in one of his anecdotal stories. I used a whole bottle and saw no difference in my skin whatsoever. Now, my upper eyelids are even a little more droopy so I'm back to giving DMAE one last shot.

Any kind of feedback or info about it would be very welcomed!!!
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Tue Oct 03, 2006 8:13 am      Reply with quote
Hi there, M.April,

The problem with the Perricone DMAE formulations is that they are many times weaker in concentration than what was shown to be effective in clinical tests. Those tests were conducted at 3% concentration, and positive results were shown after several weeks (12-16 weeks if I remember right). Perricone used such low concentrations as to be virtually useless. Confused

Skincarecentral.com has two concentrations, 2% and 4%. I use the 2% because my skin tends to be sensitive/reactive. What I do is replace my regular HA with this DMAE in HA, for moisturizing. I mix it up in the palm of my hand with a few drops of clear emu, and pat it on after my Vit C serum has absorbed, but before I put on my sunscreen. I think you were doing it right. Wink
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Tue Oct 03, 2006 9:34 am      Reply with quote
Hi PocoLoco - Thanks for your response! Did it take you 12-16 weeks to see any benefit? How would you describe your results?

Also, I'm wondering if applying it 2X/day would help or just be a waste of time and product.

And does anyone know if there are any other products or ingredients that shouldn't be used with DMAE? Or if anything diminishes or increases it's potency?

Thanks again!
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Tue Oct 03, 2006 9:51 am      Reply with quote
Hi again--

No, it didn't take me that long. But to do a true test, I should have used only DMAE and nothing else--in order to verify that any "results" I think I'm seeing came from DMAE. I'm just not patient/scientific enough to do the test properly. I still use bunches of other products like vit. C serum, emu oil, bio/gigawhite serum, etc.

Lots of people have said that they feel an immediate tightening effect from a potent DMAE serum. I have felt this too with a 3% concentration...but this does not equate to the clinical effects shown in testing. I read a summary of those and it said people had smoother, more even-toned skin, and better texture overall (at the end of the multi-week study).

Sorry if I'm not answering your question but I can't honestly say that the improvement I'm seeing has come from DMAE alone. Will I stop using it? Not on your life--it's one of the only actives with clinical data to support it.
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Tue Oct 03, 2006 10:17 am      Reply with quote
I just got my 4% from Diana Yvonne, it was on back order. I'm like Poco, use a lot of other stuff including PSF's DMAE toner but I want this for my jaw line so will be testing it mostly there. Smile

Of course, my face has improved so much (including puffy/sagging) in the last few months, I'm not sure how much better I can do in those areas but we shall see.

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Tue Oct 03, 2006 1:32 pm      Reply with quote
Hay, Since I've just started my 6% serum I'm not sure about long term eddects but I do see an immediate tightening on my jawline, but it doesn't feel tight, it just looks better. I also use it at night right after cleansing and before anything else.
Scalla.., I know you've been doing alot w/ CP serum and peels- do you attribute your improved look to one or the other or a combo. Awhile back I'd had a thread going with Molly about the CP Night eyes and how I was having alot of redness,swelling and itching, I thought it was the "uglies" and backed off to every other night w/o improve. Molly suggested it could have been an allergic rxn or sensitivity so I stopped it. I've been hesitant to try the CP serum on my face for the same reason. Thought? Thanks, Janet.
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Tue Oct 03, 2006 3:32 pm      Reply with quote
nomoreneckpain wrote:
Scalla.., I know you've been doing alot w/ CP serum and peels- do you attribute your improved look to one or the other or a combo. Awhile back I'd had a thread going with Molly about the CP Night eyes and how I was having alot of redness,swelling and itching, I thought it was the "uglies" and backed off to every other night w/o improve. Molly suggested it could have been an allergic rxn or sensitivity so I stopped it. I've been hesitant to try the CP serum on my face for the same reason. Thought? Thanks, Janet.


I'd say the improvement is due to both but different things. Peels/exfoliation to get rid of old skin and CPs for rebuilding. For an amazing reason, I seem to have stumbled on a good schedule/plan to actually see quick results. I'm yet uncertain, if it's that I'm the fastest remodeler in the West (actually East) or just that I found the right formula. I also think the CPs have firmed things up, as well. I've put an updated comparison pic for that purpose in this thread:

http://www.essentialdayspa.com/forum/viewthread.php?p=155327#155327

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Fri Oct 06, 2006 5:58 pm      Reply with quote
Hello,

I didn't know people were writing about my DMAE, but I'm happy to answer any questions!

Anyway, to answer some questions in case there are any left, it's true that Perricone sold DMAE at only 1%, while the stuff he wrote about his book was 3 or 4%!

The Johnson and Johnson clincial trials used 4% DMAE amine, which is the form I'm selling. Seriously, many people report this stuff works in a matter of DAYS, especially on the eye area. So it's easy to see from a sample if it's going to do anything for you.

The 2% is still effective (I've even used the poor bitartrate form and had some effect), and it's better if you're sensitive.

DMAE is cumulative; it's not something you want to just put on before an event. I don't know if there is benefit to using it twice a day. I guess one would have to try and see. The reason I don't recommend as general advice to most people is because this stuff is strong and CAN irritate. So once a day may be best.

That said, the formula I had made for my store hasn't irritated me at all and I use it on my eyelids, even.

I finally did add it to the main site, under the anti-aging section. Sorry I'm so behind on some things! Now to get the mandelic acid on the main page...

Kathleen
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Sat Oct 07, 2006 5:47 pm      Reply with quote
keickholt13 wrote:
Hello,

The Johnson and Johnson clincial trials used 4% DMAE amine, which is the form I'm selling. Seriously, many people report this stuff works in a matter of DAYS, especially on the eye area. So it's easy to see from a sample if it's going to do anything for you.

The 2% is still effective (I've even used the poor bitartrate form and had some effect), and it's better if you're sensitive.

That said, the formula I had made for my store hasn't irritated me at all and I use it on my eyelids, even.

Kathleen


Kathleen did you use the 2% or 4% around your eyes and your eyelids area? Drooping eyelids is one of my concerns.

Do you need to then follow up with an eye cream or gel?

I might want to add this to my order that I put through yesterday.

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keickholt13
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Sat Oct 07, 2006 9:10 pm      Reply with quote
Ninetynine wrote:
Kathleen did you use the 2% or 4% around your eyes and your eyelids area? Drooping eyelids is one of my concerns.

Do you need to then follow up with an eye cream or gel?

I might want to add this to my order that I put through yesterday.


Hi!

I use the 4$ on the entire eye area--including the eyelids. I only use it once a day. I have not found this forumula irritating so far. Most people really get good results with DMAE in the eye area. I am not just saying this b/c I sell it--even if you bought DMAE Amine from somewhere else, it would work if there was enough active in the formula. Many people see results in a matter of days!

The results are not as fast or significant with the rest of the face, but the eyes tend to respond very quickly and very noticeably.

I find it works on my neck well, too.

I hope this helps!
Kathleen
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Sun Oct 08, 2006 1:09 am      Reply with quote
keickholt, What's the diff between dmae amine and what others might sell. Is yours in a serum base or what. I have minne made up by a compound pharmacy: 4% serum. Thanks.
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Sun Oct 08, 2006 12:06 pm      Reply with quote
nomoreneckpain wrote:
keickholt, What's the diff between dmae amine and what others might sell. Is yours in a serum base or what. I have minne made up by a compound pharmacy: 4% serum. Thanks.


Hello nomoreneckpain,

DMAE Amine is the form that comes from fish and the other kind used in others' formulas is often DMAE Bibartrate. I don't know why the Amine form works better, but it does and that is what was used in the clinical trials. I HAVE had some success with the bibartrate form, too, but you need to have a very, very large % of the DMAE bibartrate in the formula and most products do not have that.

Yes, mine is a clean serum--Ingredients: DMAE Amine 4%, Citrus Hydrosol, Hyaluronic Acid

That's it. I used hydrosol instead of water. Hydrosols are just water with the essence of the active (in this case citrus) included for their active properties. Citrus Hydrosol is touted for skin tightening and firming, so that's why it's in there.

I don't know what the formula is that you are having compounded, so I can't compare the two, unfortunately. You'd have to ask the pharmacy for the ingredients if they are not listed on your bottle.

HTH,
Kathleen
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Sun Oct 08, 2006 9:09 pm      Reply with quote
thanks Kathleen Smile
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