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What causes scarring seen by some people using Retin-A ?
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William89
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Sun Mar 16, 2014 11:40 am      Reply with quote
Hi, in October I started using Retin-A 0.05% twice a week using a pea sized amount. After a month I increased it to every other night. Then after a month every night.

In mid January I noticed parts of my skin on my cheeks near my nose had many black heads, and my skin surface had small scars which were visible when the the light was shinning on my face from the side. These were not there before suing Retin-A.

Other people on this forum have referred to this an an 'orange peel' texture. During using retina-a I experienced no redness or irritation and followed the instructions with the guidance of a dermatologist through Skype conversations.

I cannot deny the evidence behind Retin-A in improving skin quality, but the results I have experienced, (after careful use) has causing worrying results to the surface of my skin. I think the outermost layer (sratum corneum) may have been thinned too much, but after reading scientific journals I still am unsure what exactly the scarring is as a result of. From reading studies, retina-a sounds incredible, which just makes my results that much more frustrating, as it just makes no sense.

Many people have attributed the scarring simply to revealing the lower layers of acne induced scar tissue. I would believe this but the scarring seems too consistent all over my face to be blamed on previous acne scaring. Also, some scars are actually concave, not convex (thin lines of raised skin).

A few people have alluded to the idea that poor health whilst using retina-a could cause the skin to not heal effectively, and the inflammation may do permanent damage.

I have been tempted to resume using retina as many people would consider my experience to be the ugly initial stage, but instinctively I think for me, and many others, this may not be the case, and continued application may make the skin worse.

Can anyone with professional knowledge in dermatology or biochemistry offer their thoughts on what may be the cause of damage seen by myself and others using retina-a (assuming the damage is not through over-application). As if we can understand the potential cause then a logical recovery regime can be created.
William89
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Mon Mar 17, 2014 9:59 am      Reply with quote
Someone on another forum has had similar issues and seemed to have cleared it up with an good anti-inflammatory skin regime:

http://www.realself dot com/review/world-fraxel-laser-orange-peel-texture-help-please-read

Also an interesting post made on this forum a few years ago -

http://www.essentialdayspa dot com/forum/viewthread.php?tid=35016

Alster agrees. “People who keep pushing the envelope with inflammation may be doing more harm than good,” she says. “When they come into my office looking very red from using Retin-A, I say, ‘Well, don’t get to that stage. Figure out what works best for you.’ ”

Like every expert interviewed for this article, Alster argues that there is more evidence in favor of acute inflammatory procedures and creams than there is against them. “We don’t know how much inflammation is good and how much is bad—that differs from person to person,” she admits. “But saying that anything that causes inflammation is bad for you? That’s really going out on a limb.”


But for me and many others, I never experienced redness or any pain what so ever, as I built up using it gradually. So, if the issue is inflammation, redness may not be the only indicator. I suspect genetics and current health status play a role in how the skin will react and heal from the inflammation caused by Retin-A.

Can anyone describe what may have happened to cause the inflammation- induced scarring. I.e what layer of skin is the scarring on/orange peel texture, had it caused uneven collagen production, or damaged the dermis?
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