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Fri Mar 27, 2015 9:13 am  |
In the book I am currently reading on Dermal Needling the Dermatologist who wrote the book advises that the damage to collagen through UV damage and intrinsic aging is different to the aging caused by glycation so that the former are caused by a loss of collagen and the latter by the abnormal stucture of collagen caused by glycation and that in the case of skin aging through glycation collagen induction can actually make things worse unless the process of glycation itself is addressed.
This has sparked a couple of questions for me:
1. How does one tell skin aging from glycation apart from UV induced or intrinsic aging?
2. What actives, supplements etc used internally and topically are effective against glycation?
3. By what method can glycation which has already occured be reversed?
If anyone has any input on these questions that would be great! |
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Fri Mar 27, 2015 9:09 pm |
1. Not sure if it's even possible to tell them apart.
2.Internal supps I use for glycation are: Benfotiamine, P-5-P, Beta-Alanine (precursor to Carnosine).
Topical actives like Tretinoin, C serum, Niacinamide, Carnosine, Idebenone.
3. There are some drugs that are said to reverse it maybe. Aminoguanidine perhaps.
Interesting discussion here: http://www.longecity.org/forum/topic/52576-reverse-glycation-what-should-one-take/ |
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Tue Mar 31, 2015 1:52 pm |
Thanks for the reply and the link Pandax. I will look into the supplements you mention, I have been taking Carnosine (also for telomere benefits) and apparently Taurine is helpful(the wikipedia page on Taurine mentions it is a glycation inhibitor) so I may look into that but would love to know what might help in reversing glycation that has already occured.
Interesting thread you link to, I see asprin is mentioned and I have read that various NSAIDs can prevent glycation in the past but of course these drugs can have serious side effects re bleeding.
I also saw this on Smart Skincare ..."Some researchers are also studying protease supplements, such as serrapeptidase or bromelain, as a possible means to break up exsiting protein-protein cross-links. Others are looking for the holy grail of anti-cross-linking: a targeted agent capable of prevent or reverse the all-important glucosepane cross-links."
http://www.smartskincare.com/aging/aging-mechanisms_glycation.html
Looks interesting but not a lot to go on. Thanks again for your reply Pandax. |
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Fri Apr 03, 2015 6:29 am |
This is an interesting topic.
Pandax, does beta-Alanine work better than Carnosine?
Has anyone used topical carnosine and found it beneficial? If so, what product or DIY formulation? I know someone who said the fine lines around their eyes improved after using carnosine eye drops.
Does anyone know how much dietary AGEs contribute to glycation issues? (AGEs present in foods from browning, Maillard reaction)
The only thing I can add is that I would use supplements on top of a good low-glycemic diet. A woman I once worked with had uncontrolled diabetes and looked about 30 yrs older than her actual age (she also suffered a lot of medical issues which probably contributed to her aged appearance, also due to her diabetes). |
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Fri Apr 03, 2015 11:22 am |
Pandex 12,
Will you share your diy serum with us? |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Fri Apr 03, 2015 11:24 am |
| Flouridation of H2O2 also causes AGE's (effecting skin as well as bones, brain tissues,etc.) |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Fri Apr 03, 2015 11:26 am |
| OOPS, i mean h2o (water) |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Fri Apr 03, 2015 8:20 pm |
| jasminerosey wrote: |
Pandex 12,
Will you share your diy serum with us? |
Idebenone- .5 grams
N-Acetyl-Glucosamine- .6 grams
Niacinamide- 1.5 grams
Butylene Glycol- .15 grams
Oil of your choice (I use Grapeseed)- 9 grams
Sea Kelp Bioferment- 9 grams
Vit.E- .3 grams
Hyaluronic Acid- .3 grams
H2O- 6 grams
Poly. 80- .6 grams
Carnosine- 1 gram
Few drops of Phenoxyethanol
I use a digital scale and a mini mixer. |
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Fri Apr 03, 2015 8:22 pm |
| Pandax12 wrote: |
| jasminerosey wrote: |
Pandex 12,
Will you share your diy serum with us? |
Idebenone- .5 grams
N-Acetyl-Glucosamine- .6 grams
Niacinamide- 1.5 grams
Butylene Glycol- .15 grams
Oil of your choice (I use Grapeseed)- 9 grams
Sea Kelp Bioferment- 9 grams
Vit.E- .3 grams
Hyaluronic Acid- .3 grams
H2O- 6 grams
Poly. 80- .6 grams
Carnosine- 1 gram
Few drops of Phenoxyethanol
I use a digital scale and a mini mixer. |
Store in fridge as this gives it a thicker consistency. |
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Sat Apr 04, 2015 12:54 pm |
| thanks Pandex12 |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Sat Apr 04, 2015 1:04 pm |
have a bit of time today. want to post more about fluoride in water supply causing AGE'S in skin
saw article on Weston Price website..makes sense to me..fluoride so insidious…difficult to get out..
for me best to shower less…or very quick showers...once a week is good if it can be tolerated with skin and hair..my diet and skin type allow me to do so w/o problems…
also i don't wear make-up..so every other day (or even more often) i can just use good quality fluoride free spring h20 to rinse face…for my skin type it works very well…(instead of using cleansing product that requires lots of water from the tap). |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Sat Apr 04, 2015 6:19 pm |
| jasminerosey wrote: |
have a bit of time today. want to post more about fluoride in water supply causing AGE'S in skin
saw article on Weston Price website..makes sense to me..fluoride so insidious…difficult to get out..
for me best to shower less…or very quick showers...once a week is good if it can be tolerated with skin and hair..my diet and skin type allow me to do so w/o problems…
also i don't wear make-up..so every other day (or even more often) i can just use good quality fluoride free spring h20 to rinse face…for my skin type it works very well…(instead of using cleansing product that requires lots of water from the tap). |
Weston Price was a very interesting man. His theory on tooth decay is spot on. I've reversed a couple of cavities following his advice.
You ever thought of investing in a shower filter that takes out fluoride?
I would not think rinsing your face with fluoridated water should be much of an issue as far as skin absorption is concerned. The heat of a shower/bath and the vapors/skin absorption would be a much bigger concern. |
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Sat Apr 04, 2015 10:03 pm |
Pandex12.
As far as I know there are no shower filters that remove fluoride effectively. Do you know of any? (ideally NFS certified). |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Sun Apr 05, 2015 8:16 am |
| jasminerosey wrote: |
Pandex12.
As far as I know there are no shower filters that remove fluoride effectively. Do you know of any? (ideally NFS certified). |
Quick Google search came up with this.
http://www.healthilluminationproducts.com/showerfilter |
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Sun Apr 05, 2015 10:09 am |
Pandex12, thanks for info..but i highly doubt that this filter removes fluoride. I thought perhaps you knew of some technology for removing fluoride.
This unit is NSF certified only for removing free chloride..and chloride in water is not free chloride….much more to say about this but no time now.
anyway, regarding fuoride…
my husband is an environmental consultant and is associated with an impeccable quality water purifier... highly certified in most areas by NSF. They used to have a fluoride removing unit but decades ago the quality of their source stopped being satisfactory and they have searched hard for a source for removing fuoride that meets NSF standards that can be incorporated in their system but cannot find one.
Honestly, reverse osmosis is the only effective way to I currently know to remove fluoride…alumina, which is often touted as adequate fluoride remover, has draw backs (this is what my dh's company used to use for fluoride removal) same for bone char filters, also touted for removing fluoride..some fluoride removal may be possible for drinking water with these devices (some drinking water filters with these materials may be NSF certified for removing 50% or so of fluoride) but it depends on individual factors like water pressure, etc. etc. (and these filters may not be adequate for removing other toxic, aging, factors in the water)
But for now, w/o reverse osmosis, re fluoride removal, showering less, soaping without the water running, etc. is the wise way to go. |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Sun Apr 05, 2015 10:15 am |
| oops. I should add that the company my dh is associated with does have NSF certified RO systems for removing fluoride, it's just that their non-RO systems do not..because, as stated, no known technology yet exists to adequately remove it. |
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71 years, primarily raw living food 35 years(vegan 45 years) herbal tea decoctions, homeopathy, TCM, facial massage, facial exercises, vacu-lifting, gua aha, shiatsu/acupressure, intention, home microcurrrent |
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Tue May 05, 2015 8:22 am |
article on glycation inhibiting herbs:
http://www.ncbi.nlm.nih.gov/pubmed/25593391
Wild caraway (not sure what exactly wild caraway is & they don't list species names), turmeric and black pepper all did a good job.
Anise has a pro-glycation effect.
The study was in vitro so who knows if it applies to real life. |
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Tue May 12, 2015 2:26 pm |
| Turmeric is an anti-inflammatory and good for the heart. I sprinkle it on my eggs. |
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